Apart from being a singer, Jay Chou is also an out-and-out e-sports fan. In April this year, Jay Chou and IDG co-founded the "Magic Jie E-sports" brand, and the first e-sports Internet cafe jointly opened by the two parties officially settled in Shenzhen.

　　The overall specification of this internet cafe is completely against the standard of high-end internet cafes, and the price is also the standard of high-end internet cafes. Some netizens visited the first Jay Chou Internet cafe in Shenzhen, and it was not cheap in terms of price. The price of the lobby was 10 yuan/hour, while the most expensive VIP seat reached 300 yuan/hour.

　　Different from other Internet cafes, the display screen, mouse, keyboard and headphones of Jay Chou Internet Cafe are all customized versions with Jay logo, and the host is a high-end game console known for its powerful game performance and high price.

　　The following private room is Jay’s exclusive private room, which is a complete copy of Jay Chou’s office in Taipei. Besides playing games, you can also enjoy the office in Jay Chou.

Compilation Shu Wang Cong

Editor: Wang Duoyu

Typesetting Shu Shui Chengwen

The long-term vision for artificial intelligence (AI) is to develop AI systems that can make major scientific discoveries, learn autonomously, and acquire knowledge autonomously.

虽然“AI 科学家”（AI scientist）这一概念还只是一种理想化的愿景，但基于智能体（agent）的AI技术的发展，为开发能够进行对话、具备反思学习和推理能力的AI智能体（AI agent）铺平了道路，这些AI智能体能够协调大型语言模型（LLM）、机器学习（ML）工具、实验平台，甚至是它们的组合。

近日，哈佛大学医学院 Marinka Zitnik实验室（高尚华博士为第一作者）在 Cell 期刊发表了题为：Empowering biomedical discovery with AI agents 的文章，系统介绍了利用 AI 智能体（AI agent）推动生物医学发现。

该文章提出了这样一个观点——“AI 科学家”可以被由人类、大语言模型、机器学习模型及其他工具（例如实验平台）组成的复合AI系统所支持的 AI 智能体（AI agent）所实现。

我们将“AI 科学家”设想为具备批判性学习和推理能力的系统，它们能够通过协作智能体整合 AI 模型和生物医学工具，并与实验平台相结合，从而为生物医学研究提供助力。

生物医学 AI 智能体不是将人类排除在发现过程之外，而是将人类的创造力和专业知识与 AI 分析大量数据、探索假设空间和执行重复性任务的能力相结合。AI 智能体将能够熟练完成各种任务，规划发现工作流程并进行自我评估，以识别并解决其知识中的差距。这些智能体使用大语言模型（LLM）和生成式模型来实现结构化记忆以进行持续学习，并使用机器学习工具将科学知识、生物学原理和理论融入其中。AI 智能体可以影响从虚拟细胞模拟、可编程的表型控制到细胞回路设计以及开发新疗法等各个领域。

The first author, Dr. Gao Shanghua, received his doctorate from Nankai University and is now a postdoctoral researcher at Harvard Medical School

The complexity of biology requires the flexibility to break down complex problems into executable tasks. AI agents can break down problems into manageable sub-tasks, which are then solved by AI agents with specific functions and integrate scientific knowledge. In the near future, AI agents can accelerate the discovery process by making workflows faster and more resource-efficient.

Leveraging AI agents to advance biomedical research

The continuous development and application of data-driven models

AI agents in the biomedical field – from LLM-based AI agents to multi-agent systems that integrate AI models, tools, and physical devices

Level of autonomy of AI agents

Cases of autonomy levels for AI agents in genetics, cell biology, and chemical biology

Core terms of machine learning

Key modules in AI agents: perception, interaction, reasoning, and memory modules

Components of a biomedical AI agent

The challenges of AI agents in biomedical discovery

AI agents can improve the efficiency of routine tasks, automate repetitive processes, and analyze large datasets to outperform current human-driven efforts in scale and accuracy. This automation allows for continuous, high-throughput research that human researchers cannot conduct individually at the same scale or speed.

Looking to the future, AI agents can provide insights beyond what traditional machine learning can achieve by making predictions across temporal and spatial scales before obtaining experimental measurements at both temporal and spatial scales. Ultimately, AI agents may help uncover new patterns of behavior in biological systems.

Original link:

https://www.cell.com/cell/fulltext/S0092-8674 (24) 01070-5

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Workers in Fuliu Fruit and Vegetable Farm in Fulin Village are transplanting corn seedlings. Photo by Yan Ningbo

Fulin Village, Dongxi Town, Qijiang District, 5 kilometers away from Dongxichang Town, has 10 villagers’ groups under its jurisdiction, with a total of 3,245 people in 961 households. In recent years, Fulin Village, taking the construction of Hemei village as an opportunity, has made continuous efforts in promoting industrial revitalization, serving the construction of major projects, and promoting the improvement of human settlements for a long time.

Prosperous industry and increasing income of the masses

At present, it is spring ploughing and sowing. In Fuliu Fruit and Vegetable Farm in Fulin Village, we can see that in the well-regulated high-standard farmland, workers are helping seedlings, covering the soil and compacting … transplanting corn seedlings into the soil, and the fields are busy. Large tracts of newly transplanted corn seedlings are green and dripping, fluttering in the sun and showing infinite vitality.

"The farm mainly grows seasonal fruits and vegetables such as corn, jar beans, green beans, lettuce, spinach, cabbage and watermelon." Peng Zongqiang, the head of Fuliu Fruit and Vegetable Farm, worked outside for a few years and had some savings in his hand. In September 2022, he responded to the call of "returning to his hometown for development" and returned to Fulin Village to transfer 46.8 mu of land to start planting fruits and vegetables at the transfer price of 500 yuan/mu.

"At that time, these lands had been transformed into high-standard farmland, and tractor roads and irrigation canals were also repaired to farms." Peng Zongqiang said that the complete infrastructure has saved a lot of time and economic costs and greatly enhanced the confidence in development. With the strong support of Murakami, the farm was soon built and put into production.

In order to increase the output of fruits and vegetables and realize large-scale and standardized production, Peng Zongqiang’s fruit and vegetable farm cooperates with Chongqing Institute of Modern Agricultural Technology and Equipment. The research institute provides technical support for the farm in soil improvement, breeding and seedling raising, fertilizer application and pest control.

"Last year, when some vegetable markets were not very good, the gross income of the farm was more than 200,000 yuan." Peng Zongqiang said frankly.

After Peng Zongqiang’s fruit and vegetable farm settled in Fulin Village, it provided employment opportunities for more than 20 villagers around. Li Yixian, 60, is one of them. As a "long-term worker" in the fruit and vegetable farm, she is responsible for turning over the soil, raising seedlings, harvesting, etc. She walks through the fruit and vegetable farm every day, which is both busy and fulfilling. "I work here, I have something to do every day, and I have a fixed income of 1,600 yuan a month." Li Yixian said.

"Next, we will cooperate with the village to build greenhouses to further expand the scale, and at the same time build corridors to turn the farm into a modern farm integrating farming experience and leisure and sightseeing, so as to drive more villagers to get rich together." Peng Zongqiang said.

In Fulin Village, Peng Zongqiang is not a case. According to Zhao Fulong, the village’s first resident secretary, in recent years, the village has continuously improved its infrastructure, introduced owners and guided farmers, and vigorously developed more than 500 mu of fruit and vegetable industries such as pepper, radish, sorghum, rape, lotus root and watermelon according to local conditions. In 2023, it achieved sales income of more than 700,000 yuan, which effectively boosted villagers’ income, and at the same time, the village collectively earned more than 50,000 yuan. In addition, the village collective also established Chongqing Xiyu Construction Labor Service Co., Ltd. to undertake projects such as canals, fire pools and village-level highway maintenance, with an annual income of over 200,000 yuan.

Service projects promote development together.

In April, at the construction site of Fulin Reservoir Project in Fulin Village, excavators waved their long arms, engineering vehicles shuttled back and forth, and construction workers performed their duties … everywhere was a scene of intense construction.

"I come here every day to have a look, and I hope it will be repaired soon." Wu Yongwan, 60, lives nearby and visits the observation deck every day. In his words, "I haven’t seen it for decades. It’s beautiful."

As a key construction project at the municipal and district levels, the total estimated investment of Fulin Reservoir Construction Project is 749 million yuan, which is a medium-sized water conservancy project with the functions of agricultural irrigation and water supply for towns and towns, and comprehensive utilization of drinking water for rural people and livestock in irrigation areas. After the project is completed and put into use, it will meet the irrigation water demand of 16,000 rural residents, 69,200 town residents and 36,800 mu of farmland in 18 villages in Dongxi, Ganshui and Zhuantang.

In recent years, Fulin Village has focused on "good governance" and made great efforts to improve the effectiveness of rural governance in accordance with the working methods of "good organization, perfect mechanism, and good publicity by the masses" and "three goodness".

Good organization means giving full play to the exemplary role of the Party organization’s fighting fortress and the vanguard of party member, demonstrating and driving villagers to be the "protagonists" in rural construction, and actively participating in the construction and development of Fulin Village. Perfecting the mechanism means establishing and perfecting the "three ones", "three musts" working method and "three guarantees" gridding mechanism, so as to resolve various contradictions and disputes in the bud and achieve "everything has an explanation, everything has a landing, and everything has an echo". The masses promote kindness, that is, fully mobilize the enthusiasm of the masses to participate in self-government, set up a "Fulin Sunset Red" volunteer service team, carry out various volunteer services around the needs of villagers, and set up a village-level parliamentary hall to form a new pattern of rural governance that "everyone has something to discuss, talk about it together, and help together when it is difficult".

Renovating the environment and "refreshing" the village face

Fangfei in April, the spring is bright and warm. A winding country road runs from the head of Fulin village to the end of the village. Along the way, surrounded by clear water, birds singing and flowers fragrant, a patchwork of houses, a clean and bright small courtyard, and a unique wall painting … what a beautiful and peaceful picture of the countryside.

"Every household builds a garden, roads are swept and garbage is collected." Speaking of Fulin Village today, Zhao Fulong is like a few treasures. Since 2022, with the support of the Agricultural and Rural Committee of Qijiang District and the government of Dongxi Town, Fulin Village has invested 2 million yuan to upgrade the overall living environment of the village. After that, Fulin Village has changed its former appearance and its face value has improved significantly.

In order to continuously consolidate the improvement effect of human settlements and create a clean, tidy and orderly human settlements, Fulin Village regards the participation of human settlements and village-level public welfare undertakings as an important criterion for party member and the masses to evaluate the quality, and actively carries out the selection of "demonstration households of human settlements", "Hemei families", "civilized households" and "sanitary households" to fully mobilize the enthusiasm of the masses and form a good situation in which everyone participates in the improvement and maintenance of human settlements.

"Now not only is the village clean, but the villagers’ consciousness has also improved." Pu Degui, a 58-year-old villager, bought a house in Chongqing and wanted him to go to the city to enjoy himself. Feeling the changes in the village in the past two years, Pu Degui said frankly: "I don’t want to go to town. If you have nothing to do, you can get flowers at home, wait for the grass, or go out and have a look, which is particularly comfortable. "

"In the next step, we will firmly seize the opportunity of the construction of Fulin Reservoir, incorporate the ladder homestay, the Four Seasons Fruit Garden and the trail around the lake into the development plan of our village, and combine the characteristics of Fulin to create an recognizable brand of Fulin agricultural tourism, promote rural revitalization, and make the villagers feel more, happier and more secure." Zhao Fulong said. (Qin Ningbo, Wang Yu, Gu E)

　　China News ServiceBeijing, July 14th (Reporter Gao Kai) According to the real-time data of Lighthouse Professional Edition, as of July 14th, the box office (including pre-sales) of China mainland movies in 2023 exceeded 30 billion yuan (RMB, the same below), which was close to the total box office of 30.067 billion yuan in 2022.

　　According to the data of Lighthouse Professional Edition, up to now, the top five films at the box office in 2023 are: Man Jiang Hong (4.544 billion yuan), The Wandering Earth (4.029 billion yuan), Disappeared She (3.263 billion yuan), Bear with Me (1.495 billion yuan) and Octagon.

　　In addition, Unfamiliar Road of Life, Speed and Passion 10, Unknown, Deep Sea and King of the Sky rank six to ten respectively.

　　Since the Spring Festival this year, the domestic film market has shown a rapid recovery trend, and the box office performance of domestic films is particularly prominent. At present, among the top ten films at the box office, domestic films occupy nine of them and occupy the top five seats, which fully shows their dominant position in the cinemas in China.

　　Since entering the summer file, domestic films such as Disappeared She, In an Octagonal Cage and Three Wan Li in Chang ‘an have continuously triggered a movie-watching craze here. The data shows that as of the 14th, the box office of this summer file has exceeded 7.8 billion yuan.

　　On this basis, in late July, a number of films with box office appeal will be released soon, and the summer file is considered to be very likely to have further bright performance.

　　Among them, the comedy "Super Family" produced by Mahua FunAge announced the final file on July 21. As of press time, the number of people who want to see the film in the lighthouse professional edition has exceeded 860,000; Directed by Dapeng and starring Bo Huang and YiBo, the drama "Enthusiasm" is scheduled for July 28th. At present, the number of people who want to see it has reached 610,000. In addition, the huge fantasy costume blockbuster "Feng Shen I" was finalized on July 20, which attracted people’s attention with its all-star cast, mysterious scenes and adaptation of the story of "Feng Shen Romance". At present, the number of people who want to see the index has reached nearly 470,000.

　　The industry believes that the monthly box office in July 2023 is expected to break through the 7 billion yuan mark, creating a new box office record in the same month in China’s film history.

　　The Spring Festival is approaching, and the population is flowing in large numbers, so the number of people who work in cities and return home to visit relatives for holidays will increase rapidly. This has also brought severe challenges to the treatment of rural COVID-19.

　　"Grassroots medical and health institutions have undertaken a large number of tasks of first diagnosis of patients and classified management of key populations." On January 14th, Nie Chunlei, director of the Department of Primary Health and Health in National Health Commission, said that there was an imbalance in medical resources between urban and rural areas, with obvious differences, and health service resources in rural areas were relatively insufficient. "Grassroots village doctors urgently need to master the knowledge and skills of Covid-19 infection diagnosis, severe early warning and treatment, especially the use of antibiotics, hormones and small molecule drugs, so that patients can be effectively treated."

　　On January 11th, the General Practice Branch of Chinese Medical Association, together with several branches, issued the "Guidelines for Diagnosis, Treatment and Service of Infections in novel coronavirus (First Edition)" (hereinafter referred to as the "Guidelines"), which elaborated on diagnosis, clinical classification, identification, treatment and treatment of severe cases.

　　How to warn of moderate and severe diseases?

　　"For the grassroots, the evaluation of COVID-19’s diagnosis and clinical typing is more important, and it is also the whole of the diagnosis and treatment strategy." Wu Hao, the correspondent of the Guide and dean of the School of General Practice and Continuing Education of Capital Medical University, said.

　　In the evaluation of patients’ clinical typing, Wu Hao said that the majority of grassroots village doctors need to pay special attention, and the evaluation of vital signs can be carried out through a simple "four-piece set" of body temperature, respiration, heart rate and blood pressure; In the measurement of finger oxygen saturation, due to the low outdoor temperature in winter, the village doctor found that the patient’s limbs or skin were cold, and its oxygen saturation value may be less than 93%, but this does not mean that the patient is at risk, and it is necessary to judge by observing whether the lips are purple and dry.

　　Imaging examination can be based on chest X-ray or CT. If there is pneumonia in COVID-19, most of it occurs in the lower lungs. If there is no CT in rural medical institutions, you can auscultate whether the patient’s lower lungs are accompanied by wet rales (if there is, CT examination is not necessary); Instead of taking X-ray chest film, you need to pay attention to the patient’s posterior and anterior and lateral films, and sometimes you can see some exudative and inflammatory lesions. Although the X-ray chest film may miss the diagnosis, if the chest film shows pneumonia, the actual situation of the patient will be more serious.

　　"What needs to be repeatedly emphasized is the early warning of severe illness." Wu Hao said that the patient’s three situations indicate that it is very dangerous and may progress to severe illness. First, moderate and severe dyspnea occurred, including (meeting one of the following conditions) heart rate greater than 120 beats/min, breathing frequency greater than 30 beats/min, and breathing with an auxiliary ventilator (pay attention if the patient cannot speak a whole sentence during the consultation); Second, the oxygen saturation is lower than 93%; In addition, if the patient has chest pain, falls, changes of consciousness, low blood pressure, decreased urine output, severe vomiting or diarrhea, etc., we should also consider severe warning.

　　Zhang Wenhong, director of the Department of Infectious Diseases of Huashan Hospital affiliated to Fudan University, said during the training that after the implementation of the "Class B and Class B Management" policy, it is crucial for grassroots doctors to master the transformation from Chinese diseases to severe diseases in the process of normalizing COVID-19 treatment. In particular, the clinical classification of patients was adjusted in the "novel coronavirus Infection Diagnosis and Treatment Program (Trial Tenth Edition)", instead of ordinary type, it was medium. "Light and medium-sized should be treated at the grassroots level. Therefore, the grassroots should prevent medium-sized to heavy-duty, and heavy patients need to be referred in time. "

　　Zhang Wenhong said that in the clinical early warning of severe illness, one indicator has changed and it is necessary to be alert to the deterioration of the patient’s condition, that is, the patient is "hypoxic after activity; After slight activity, the oxygen saturation value is less than 94%, which can make the patient walk back and forth in the corridor. If his CRP(C-reactive protein), lactic acid and other indicators are normal, it means that the oxygen saturation value has decreased, which is also a signal of the progress of the disease.

　　How to use hormones and antibiotics?

　　Is it really effective for rural doctors to use the four-piece set of "antiviral+antibiotic+hormone+antipyretic"?

　　Wu Hao explained that, in fact, the elderly people in rural areas were not treated in time after onset, and there was malnutrition. When he went to the clinic for medical treatment, he might be in the acute pneumonia period, and even had a bacterial infection. At this time, the village doctor will give hormone and antibiotic treatment, and the effect will be more obvious.

　　Regarding whether antiviral drugs can be used for more than 7 days, Wu Hao said that the time of viremia is usually 7 days. The reason why antiviral drugs are prescribed to be used within 5 days of onset is because the earlier they are used, the greater the benefit, which also takes into account the incubation period of 1 ~ 2 days. "For the elderly and frail patients, the process of virus clearance is slow. At this time, even if the illness lasts for more than 7 days, it will still be effective to continue using antiviral drugs."

　　Wu Hao further said that the use of antibiotics should also avoid blindness and should be judged with reference to the patient’s indications. For example, if the patient coughs dry or coughs white sputum, or has less sputum in the early stage, this is a viral infection; If the patient has pus or coughs yellow sputum, it is generally a bacterial infection. If the village doctor doesn’t have the above-mentioned accurate detection means, he can write it all in combination with the patient’s situation, that is, his family members are infected and have flu symptoms, and he also has lung symptoms, which is definitely viral pneumonia, but if his family members don’t have it, it is the possibility of community-acquired pneumonia.

　　In order to facilitate the operation of primary doctors, the "Simplified Edition" published on January 4th referred to the "four-step" treatment of COVID-19 at the primary level: general treatment, oral small molecular antiviral drugs, glucocorticoid, oxygen therapy and respiratory support.

　　Therefore, Zhang Wenhong emphasized that glucocorticoid should be used with great caution. It is suitable for COVID-19 patients with high-risk factors (older, with medium-sized clinical manifestations and evidence of disease progression). At this time, low-dose and short-term corticosteroids can be given. "Specific usage, you can use dexamethasone or prednisone, 4 ~ 6 tablets a day, eat for 3 days. Within 72 hours, the patient will face a turning point. If the patient gets better quickly, it will be reduced to 2-3 tablets and taken for another 3 days. If it is relieved later, either stop taking the medicine or use another tablet for 3-4 days. If the patient progresses to severe illness, he needs to be hospitalized for observation, and the dosage of hormones can also be increased, and the treatment plan for severe patients can be started later. "

　　"On the one hand, an early British clinical study showed that the daily use of 6 mg dexamethasone in large-scale hospitalized patients in COVID-19 can reduce the mortality rate; On the other hand, our team also gives patients low doses of hormones in the early stage of severe illness, which can greatly reduce the intubation rate of patients and reduce the mortality rate. " Zhang Wenhong said.

　　The Guide stipulates that glucocorticoid can be used for patients with early onset in the community, such as high-risk factors such as basic diseases and advanced age, or medium-sized patients who need oxygen therapy, after evaluating the contraindications of hormone use.

　　Zhang Wenhong said that "prone position ventilation treatment" for COVID-19 patients can be operated regardless of the resources of rural medical institutions, and it is suitable for medium-sized patients with severe high-risk factors and rapid progress. This is also recommended by many respiratory and critical care experts.

　　"When the patient is lying on his back, the heart and lungs are under certain pressure, and there will be problems in the proportion of ventilation blood flow. After prone, the pressure on the heart and lungs is reduced, the proportion of ventilation blood flow will be more balanced, and the physiological diseases related to inflammation of patients will also get better. " Li Yingchuan, an expert in critical care medicine and vice president of Shanghai Tenth People’s Hospital, explained to reporters earlier.

From 0: 00 to 24: 00 on May 8, there were no newly reported local confirmed cases, suspected cases and asymptomatic infected persons.

From 0: 00 to 24: 00 on May 8, there were no new reports of imported confirmed cases, suspected cases and asymptomatic infected persons.

Yan’ an Baota district coping with epidemic prevention and control work headquarters

About announcing the addition of a close contact

Announcement of main activity tracks

On May 6th, according to the information feedback from the regional investigation platform of Shaanxi Province, one person in Baota District of Yan ‘an City was a passenger in the same carriage as the first screening positive person in COVID-19, Henan Province, and was judged as a close contact of the first screening positive person in COVID-19. At present, centralized isolation medical observation has been implemented in Baota District. Now the main activity track of this close contact in Baota District is notified as follows:

According to epidemiological investigation, the main activity tracks of close contacts are as follows:

May 5: From 10: 23 to 14: 02, Xi ‘an Railway Station arrives at Yan ‘an Railway Station by K5446 train (No.21 middle berth in 3 carriages); From 14: 30 to 15: 00, eat at the haggis restaurant next to the railway station; At 15:20, check into Yilai Hotel opposite the railway station; 20:20-20:51 Dinner at Hujia Laoda Meat Sandwich Shop near Yilai Hotel.

May 6th: Dine in the restaurant on the second floor of Yilai Hotel at 8:30; 9:48-12:30 Yinjiagou Real House activity; 12:45-13:05 Dining with spicy liver on the opposite side of Ouyada Building Materials Market in Yinjiagou Triumph City; 13:10-15:00 Yinjiagou Arc de Triomphe Ouyada Building Materials Market Activity; 15:12-15:50 Moon Star Home Market Activities on 100m Avenue; 16:11-16:53 Daming Palace Building Materials Market (Xincheng Store) activity; At 17:25, he returned to Yilai Hotel, and then he was placed in centralized isolation for medical observation.

Please take the initiative to report to the unit, the residential community (village) or the disease control department in a timely manner, and implement the 7-day health monitoring and 3 times (the first, fourth and seventh days) nucleic acid detection measures. At the same time, the general public are requested to pay attention to the information released by the relevant authorities at any time, not to believe in rumors, not to spread rumors, to further raise their awareness of personal protection, to wash their hands frequently, to wear masks, and to maintain a safe social distance. Those who conceal, falsely report or fail to cooperate with the control and control, resulting in the spread of the epidemic, will be investigated for legal responsibility according to law.

Xi’ an CDC issued a reminder

At present, there are many local epidemics in COVID-19, and the situation of prevention and control is still severe and complicated. Hou Tiejun, an expert on immunization planning at the Center for Disease Control and Prevention in Xi ‘an, reminded that with the popularity of Omicron mutant, there will be more and more asymptomatic infected people because of its characteristics of faster spread and stronger concealment, and the improvement of vaccination coverage. If asymptomatic infected people return home, it is bound to bring infection risk to the elderly at home.

At present, the national vaccination strategy is based on high-risk groups and key groups, and finally gradually transition to the elderly over 60 years old. "Vaccination with Covid-19 vaccine is still an effective means of protection at this stage, especially to accelerate the Covid-19 vaccination rate for the elderly, especially the very old. Only by improving the vaccination rate of the elderly can we truly win the initiative and win time for the prevention and control of the epidemic. " Hou Tiejun said.

Vaccination can effectively reduce the elderly.

Morbidity and mortality in COVID-19

According to the epidemic situation in other regions and provinces in China, the mortality rate and hospitalization rate of the elderly are very different whether they are vaccinated or not, especially the mortality rate can be more than ten times. If the elderly are not vaccinated or vaccinated with booster shots, such a population will lead to an increase in the overall incidence. Therefore, experts suggest that if the elderly have no absolute contraindications to vaccines, they should take the initiative to vaccinate COVID-19 vaccine as soon as possible.

In modern society, transportation is more convenient and people flow more frequently. No place is isolated from viruses. Hou Tiejun said, "At present, the mutated virus imported in some areas is highly contagious, and some cases have atypical clinical manifestations or even asymptomatic infected people. Even if the elderly do not go out at home or live in remote rural areas, they may still be infected with the virus. Especially if other people in the family work and study outside and have more opportunities to contact with others, it is possible to bring the virus home and cause infection in the elderly. " Therefore, in order to avoid threatening the lives of the elderly and causing a burden to the family and society, the elderly should also "take over everything" as soon as possible, which is to protect themselves and others.

It is also very necessary for the elderly to get booster shots. According to the research results on the safety, immunogenicity, effectiveness and immune persistence of the vaccine, at present, one dose of booster immunization is recommended for people over 18 years old who have completed basic immunization with inactivated vaccine and adenovirus vector vaccine in China, and it has been implemented nationwide. Because the immune function of the elderly is relatively weak, the antibody level and protective effect produced by people over 60 years old after completing the basic vaccine immunization are relatively lower than those of people aged 18 to 59, and once infected, the proportion of severe and critical diseases is also high. Therefore, it is suggested that the elderly should not only complete the whole process of basic immunization as soon as possible, but also strengthen immunization six months after the completion of basic immunization in order to obtain better protection effect. Studies have shown that the risk of serious illness and death caused by Covid-19 infection can be reduced by more than 90% after the elderly are vaccinated with booster immunization.

"Homologous" and "Sequential" Strengthening Methods

Can effectively prevent viruses.

So should the elderly choose homologous immunization or sequential immunization? In this regard, Hou Tiejun said that homologous booster vaccination means that the vaccine with the same technical route used in the original basic immunization is used to complete booster vaccination. Simply put, the inactivated vaccine was used before and the third booster vaccine was continued. Sequential immunization booster vaccination, that is, the booster vaccination is completed with a vaccine with a different technical route from that used in the original basic immunization. "For example, after the inactivated vaccine, we use adenovirus vaccine to strengthen. In this case, we can choose the booster according to the vaccine situation of the outpatient clinic, the specific actual situation of the recipient, and the actual advice of the pre-inspection doctor. However, both strengthening methods can effectively prevent viruses. We also appeal to elderly friends who have not been vaccinated to get vaccinated as soon as possible. "

Some elderly people mistakenly think that they are older and are more likely to respond to vaccination. But it turns out that the adverse reaction rate of the elderly after vaccination is far lower than that of the young. Because the old people’s immune system sensitivity is relatively low compared with young people, and they are less likely to respond. At present, the oldest person vaccinated abroad is 106 years old, and China is 109 years old. China has vaccinated more than 3 billion doses, and the results prove that it is very safe for the elderly to vaccinate.

For the elderly people with basic diseases

What should I pay attention to when vaccinating Covid-19 vaccine?

First, when the elderly are vaccinated, if they have a basic disease, it is recommended to vaccinate in a stable period. If they are not sure, it is recommended to consult a vaccination doctor or a clinician to assess whether they can be vaccinated with Covid-19 vaccine.

Second, know the vaccination process and related knowledge in Covid-19 in advance, and make an appointment in advance to avoid the fatigue and tension caused by the elderly waiting too much at the scene. During the vaccination process, it is recommended that the elderly be accompanied by their families to prevent accidents and falls.

Finally, the elderly need to stay under observation for 30 minutes after being vaccinated with Covid-19 vaccine. If you feel unwell after vaccination with Covid-19 vaccine for a long time, you are advised to seek medical advice as soon as possible. If you suspect that it is related to Covid-19 vaccine, you should also report it as soon as possible.

Source: Shaanxi Provincial Health and Health Commission

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Original title: "Emergency search! The trajectory involves Xi ‘an Railway Station, restaurants, building materials market, and the latest bulletin of Shaanxi Provincial Health and Health Commission! 》

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[Important events]

Suning.cn: Planning to issue shares to purchase assets will be suspended tomorrow.

Suning.cn (002024) announced that it plans to issue shares to purchase assets. The assets to be purchased are the equity of the project company held by Suning Yunxin Private Equity Fund of Shenzhen Venture Capital. The company’s shares will be suspended from June 23, 2021.

Shanghai Lingang: It is planned to invest in the establishment of G60 Science and Technology Innovation Economic Development Group in Shanghai Yangtze River Delta.

Shanghai Lingang (600848) announced that the company plans to jointly establish Shanghai Yangtze River Delta G60 Kechuang Economic Development Group Co., Ltd. with Songjiang SDIC and Xinmin Assets. The registered capital of G60 Kechuang Group is planned to be RMB 3 billion, and the Company plans to contribute RMB 1.5 billion, accounting for 50% of the registered capital of G60 Kechuang Group.

Lishang Guochao: Termination of the wholly-owned subsidiary’s participation in Palmetto, a medical beauty company.

Lishang Guochao (600738) announced that Lishang Holdings, a wholly-owned subsidiary of the company, terminated the signing of the Capital Increase Agreement between Lishang Guochao (Zhejiang) Holdings Co., Ltd. and Sichuan Medical Jimei Biotechnology Co., Ltd. on Pameiduo (Chengdu) Biotechnology Co., Ltd. The company has not yet signed a capital increase agreement and failed to fulfill its actual capital contribution obligations. Termination of this foreign investment will not adversely affect the company’s business development and financial status.

Hanma Technology: Geely Commercial Vehicle Group is planning the divestiture of the company with Maanshan Municipal Government.

Hanma Technology (600375) disclosed the announcement of stock price change, saying that Geely Commercial Vehicle Group, the controlling shareholder of the company, and Li Shufu, the actual controller, are planning the divestiture of the company with Maanshan Municipal Government in order to further focus on the main business, integrate strategic resources, optimize the industrial structure and revitalize effective assets, which is of great uncertainty. In addition, there are no other major issues that affect the fluctuation of the company’s stock price.

Chanz Education: At present, all courses related to the company’s HarmonyOS system have not been charged, and other businesses related to HarmonyOS have not generated income.

Chanz Education (003032) replied to the letter of concern of Shenzhen Stock Exchange, saying that up to now, all courses related to the company’s HarmonyOS system have not been charged, mainly for public welfare and promotion; At present, the company’s other businesses related to HarmonyOS system have not generated income, which will not affect the company’s recent performance.

Zhongxing Fungus Industry: Received a letter of concern to explain the feasibility of cross-border acquisition of Shengjiao wine industry.

Zhongxing Fungus Industry (002772) received a letter of concern from Shenzhen Stock Exchange, asking the company to explain the funding arrangements for the proposed acquisition of the equity of Shengjiao Liquor in cash, and demonstrate whether the company has sufficient payment capacity and the impact of raising funds to acquire the equity of Shengjiao Liquor on the company’s financial situation; Explain the feasibility of the company’s cross-border acquisition of Shengjiao wine industry and its future integration plan, whether Shengjiao wine industry can form synergy with the company’s existing business, whether the company has sufficient ability to manage wine industry assets, and whether it can effectively control the underlying assets.

Bowei alloy: 337 investigation will not have a substantial impact on the company’s production and operation.

Bowei Alloy (601137) announced that Advanced SiliconGroup Technologies of the United States filed an investigation application with the United States International Trade Commission (ITC) in accordance with Section 337 of the United States Tariff Act of 1930. According to the company’s internal verification, this survey involves six patents of the applicant, which may involve the company’s silicon photovoltaic cells and components, at least one of which is related to nanostructure. According to the preliminary judgment, the products involved in the survey have no substantial impact on the company’s current operation.

Shenzhen Datong: The "Datong Media Eco-chain" developed by the company has obtained blockchain filing.

Shenzhen Datong (000038) announced that the National Network Information Office recently issued the Announcement on Issuing the Record Number of the Fifth Batch of Domestic Blockchain Information Services, and the "Datong Media Ecological Chain" developed by the company was successfully filed with the record number "Guangdong Net Xinbei 44030521866417370023".

Dongfang Zirconium Industry: Some research reports only represent analysts’ personal views on the company’s performance forecast.

Dongfang Zirconium Industry (002167) announced the abnormal fluctuation of stock trading, and the deviation of the closing price increase of the company’s stock for three consecutive trading days exceeded 20%. Recently, the company has paid attention to the prediction of the company’s future performance, net profit, price-earnings ratio and other indicators in the research reports issued by some companies. Now the risks are as follows: Some research reports only represent the personal views of analysts, so investors are advised to invest rationally and pay attention to risks.

Yuneng Holdings: The reorganization will be held on June 23, and the stock will be suspended from June 23.

Yuneng Holdings (001896) announced that the M&A and Reorganization Committee of CSRC will hold a working meeting on June 23 to review the company’s issuance of shares, payment of cash to purchase assets, raising matching funds and related transactions. The company’s A shares have been suspended since the market opened on June 23rd.

*ST Shen Ji: The court ruled that the holding subsidiary went bankrupt.

*ST Shenji (000410) announced that Shenyang Bucata Weibo Machine Tool Co., Ltd. (hereinafter referred to as "BW Company"), a holding subsidiary of the company holding 50% of the shares, received the Civil Ruling from the Shenyang Intermediate People’s Court and ruled that BW Company was bankrupt.

Huaxia Happiness: The company failed to repay the debt principal and interest on schedule, totaling 66.99 billion yuan.

Huaxia Happiness (600340) announced that the company and its subsidiaries recently increased the amount of debt principal and interest in the form of bank loans, trust loans and other debts that failed to repay as scheduled by 6.449 billion yuan. As of June 21, the company has failed to repay the debt principal and interest as scheduled, totaling 66.99 billion yuan. At present, the company is actively coordinating matters related to the extension with financial institutions involved in failing to repay the principal and interest of debts as scheduled.

Osekan: Dilalos dispersible tablets obtained drug registration approval.

Osekan (002755) announced that the company’s subsidiary Jiangsu Osekan Pharmaceutical Co., Ltd. recently obtained the drug registration approval in National Medical Products Administration.

Luoxin Pharmaceutical Co., Ltd.: Lansoprazole for injection passed the quality and efficacy consistency evaluation of generic drugs.

Luoxin Pharmaceutical (002793) announced that lansoprazole for injection of Shandong Yuxin, a subsidiary of the company, passed the consistency evaluation of generic drug quality and efficacy.

Buchang Pharmaceutical: Suspension of clinical trial of BC0335 granules

Buchang Pharmaceutical (603858) announced that Shandong Danhong Pharmaceutical Co., Ltd., a wholly-owned subsidiary, had received the Notice of Suspension of Clinical Trials on BC0335 Granules issued by National Medical Products Administration. According to the Drug Administration Law of People’s Republic of China (PRC), the Measures for the Administration of Drug Registration and the Standard for the Evaluation and Management of Safety Information during Drug Clinical Trials (Trial), there is a great safety risk in BC0335 granules at present, and all clinical trials should be suspended immediately. This suspension of clinical trials will not have a significant impact on the current and future operations of the company and its holding subsidiaries.

Nanfeng shares: It is planned to sell 100% equity of ZTE Energy Equipment for RMB 1.062 billion.

Nanfeng Co., Ltd. (300004) announced that the company intends to sell 100% equity of ZTE Energy Equipment Co., Ltd. held by the company to related party Yifan Technology through cash sale. This transaction constitutes a major asset restructuring. The transaction price of the underlying assets of this major asset sale is determined to be 1.062 billion yuan.

Enjie shares: It is planned to purchase 4.78% equity of Shanghai Enjie by issuing shares and paying cash.

Enjie shares (002812) announced that the company intends to purchase 3.25% equity and 1.53% equity of Shanghai Enjie held by Yan Ma and Alex Cheng by issuing shares and paying cash. The estimated price of the underlying assets of this transaction is 2.342 billion yuan. At the same time, it is planned to issue shares to no more than 35 specific investors to raise matching funds of about 1.542 billion yuan.

*ST Langqi: As of June 21, new debts were overdue by 240 million yuan.

*ST Langqi (000523) announced that as of June 21, 2021, the new debts of the company and its subsidiaries were 240 million yuan overdue, accounting for 9.27% of the absolute value of the company’s latest audited net assets, and the overdue debts totaled 761 million yuan, accounting for 29.42% of the company’s latest audited net assets.

*ST Cody: Signed a strategic cooperation agreement with Beijing Zhiyun

*ST Cody (002770) announced that the company signed the Strategic Cooperation Agreement with Beijing Zhiyun on June 21 to establish a strategic partnership. The two sides intend to carry out all-round strategic cooperation in the fields of investment and financing, industrial mergers and acquisitions, business resource integration, etc., so as to comprehensively improve operational efficiency, enhance comprehensive market competitiveness, and achieve mutual benefit and win-win results.

Hongqi chain: use its own idle funds of 100 million yuan to purchase bank wealth management products.

Hongqi Chain (002697) announced that the company used its own idle funds of 100 million yuan to purchase the "China Industrial and Commercial Bank of China linked exchange rate range cumulative corporate RMB structured deposit product-special account type L, No.173, 2021" issued by ICBC.

Offshore Oil Development: Signed a contract with SKI for integrated services of FPSO in Lufeng 12-3 Oilfield.

CNOOC Development (600968) announced that the company signed a contract with SKI for the integrated service of FPSO in Lufeng 12-3 Oilfield. According to the project price and rate table in the contract and the 10-year service period, the amount involved in the contract is about 4.4 billion yuan (including tax). The signing of the contract is conducive to further expanding the scale and market share of the company’s FPSO, and enhancing the company’s profitability and anti-cyclical ability.

Changchun High-tech: Jinsai Pharmaceutical, a subsidiary, plans to acquire 51% equity of Beijing Xinyuan Changqing.

Changchun High-tech (000661) announced that Jinsai Pharmaceutical, a subsidiary of the company, signed the Agreement on Capital Increase, Share Expansion and Equity Transfer of Beijing Xinyuan Changqing Biotechnology Co., Ltd. with Beijing Xinyuan Changqing, Zhonghai Yangyi and Huaying Changqing. Jinsai Pharmaceutical intends to acquire 51% equity of Beijing Xinyuan Changqing in two stages with its own funds in the form of capital increase and share expansion and acquisition of part of the original shareholders’ equity. According to the research and development progress of Beijing Xinyuan Changqing related projects, the total investment is estimated to be 113.3 million yuan-206.2 million yuan.

Beijing Kerui: It is planned to acquire 100% equity of Beijing Institute of Technology Lutong New Energy Car Rental Co., Ltd.

Beijing Kerui (002350) announced that the board of directors of the company deliberated and passed the proposal, agreeing that Kerui Energy, a wholly-owned subsidiary, acquired 100% equity of Beijing Institute of Technology Lutong New Energy Car Rental Co., Ltd. through the Beijing Stock Exchange with its own funds of 7,304,300 yuan. Through this equity transfer, on the one hand, we can obtain the relevant qualifications of Beijing Institute of Technology Lutong New Energy Car Rental Co., Ltd., which is conducive to the development of Kerui Energy’s subsequent new energy business and charging pile business, on the other hand, we can obtain its 30 new energy vehicles and their corresponding 30 new energy vehicle licenses.

Lake Electric: It plans to acquire 100% equity of Shanghai Pajie Auto Parts Company.

Lake Electric (603355) announced that the company intends to acquire 100% equity of Shanghai Pajie Auto Parts Co., Ltd. The total valuation range is expected to be between 1.243 billion yuan and 1.464 billion yuan.

Aoyuan Meigu: The reserve price of assets to be publicly listed and transferred is 1.02 billion yuan.

Aoyuan Meigu (000615) announced that the company intends to transfer 100% equity of Jinghan Real Estate, 100% equity of Beijing Yangjia and 35% equity of Penglai Pension held by the company through public listing on Beijing Equity Exchange. The company plans to use 1.02 billion yuan as the reserve price for listing, and the final transaction price will be determined according to the results of public listing.

Shandong Luqiao: The subsidiary plans to invest 45 million yuan to participate in the establishment of Shangao Factoring Company.

Shandong Luqiao (000498) announced that Luqiao Investment, a subsidiary of the company, plans to jointly establish Shangao Commercial Factoring (Beijing) Co., Ltd. (tentative name) with Shangao Shenzhen Investment and Beijing. Shangao Factoring Company has a registered capital of 100 million yuan, of which Luqiao Investment contributed 45 million yuan, accounting for 45% of the equity of the joint venture company. Sunco Shenzhen Investment is a wholly-owned subsidiary of China Shandong Expressway Financial Group Co., Ltd., the controlling shareholder of the company, and this transaction constitutes a connected transaction.

Shuobeide: Jiangsu Kaier, a holding subsidiary, plans to invest in the biometric module project.

Shuobeide (300322) announced that Jiangsu Kaier, a holding subsidiary of the company, plans to sign the Investment Agreement for the Project with an Annual Output of 100 Million Biometric Modules with the Management Committee of Lujiang High-tech Industrial Development Zone in Hefei, Anhui. The agreement stipulates that Jiangsu Kaier will invest in Lujiang High-tech Zone with an annual output of 100 million biometric modules, with a total investment of 300 million yuan. After the project is put into production, it is estimated that the annual output value will reach 500 million yuan.

Yingliu Co., Ltd.: set up a subsidiary to develop advanced heavy-duty gas turbine core thermal components and key materials.

Yingliu Co., Ltd. (603308) announced that in order to aim at the advanced manufacturing technology of core thermal components of international leading heavy-duty gas turbines and accelerate the research and development of advanced high-temperature alloy core thermal components and key materials of gas turbines, the company invested and established Yingliu Gas Turbine Components Innovation Center (Shenzhen) Co., Ltd., a wholly-owned subsidiary, with a registered capital of 50 million yuan.

[Increase or decrease holding]

Yushun Electronics: Chairman Zhou Lu increased his holding of 300,000 shares of the company.

Yushun Electronics (002289) announced that Zhou Lu, the chairman of the company, increased his holding of 300,000 shares of the company by centralized bidding with his own funds on the same day, with a total holding amount of 2.921 million yuan. After the increase, Zhou Lu accumulated 300,000 shares, accounting for 0.1070% of the company’s total share capital.

Sega Technology: The controlling shareholder and others promise not to reduce the company’s shares in the next six months.

Sega Technology (002796) announced that the company’s controlling shareholders, actual controllers Han Yuyu, Han Huiming and Wang Juan (the three are acting in concert) and Chen Baohua, the shareholder, director and senior executive who holds more than 5% of the company’s shares, had previously promised not to reduce the company’s shares from December 25, 2020 to June 24, 2021. After the above commitments expire, the above shareholders promise not to reduce their shares in the company through centralized bidding or block trading within the next six months (that is, from June 25 to December 24, 2021).

Gujia Home Furnishing: Senior executives plan to increase their holdings by 30 million yuan to 60 million yuan.

Gu Jiaju (603816) announced that Ou Yafei, a senior manager of the company, or the limited partnership, trust plan and asset management plan he participated in, intends to increase the company’s shares, and the amount of shares to be increased is not less than 30 million yuan and not more than 60 million yuan. The overweight price shall not exceed 100 yuan/share.

Lanying Equipment: The controlling shareholder and its concerted parties intend to reduce their holdings by no more than 1%.

Lanying Equipment (300293) announced that Lanying Auto Control, the controlling shareholder of the company, and China Giant International, acting in concert, plan to reduce their holdings of the company’s shares by centralized bidding within three months after fifteen trading days (1% of the company’s total share capital).

[View performance]

Vanadium and titanium in Panzhihua Iron and Steel Company: It is estimated that the net profit in the first half of the year will increase by 426%-519% year-on-year.

Pangang Vanadium and Titanium (000629) announced that the net profit in the first half of the year is expected to increase by 426%-519% year-on-year. During the reporting period, the company’s titanium dioxide market was in a strong boom period, and the vanadium product market continued to improve. Both the price and sales volume of vanadium and titanium products achieved a significant year-on-year increase.

Liard: The net profit in the first half of the year increased by 11%-34% year-on-year. In the first half of the year, the domestic market demand continued to be strong.

Liard (300296) disclosed the semi-annual performance forecast for 2021, and estimated the net profit for the first half of the year to be 250-300 million yuan, up 11.27%-33.52% year-on-year. In the first half of the year, the domestic market demand continued to be strong, and the newly signed orders increased significantly compared with the same period of last year, and exceeded the order scale in the same period of 2019, creating a record high.

CITIC Special Steel: The net profit in the first half of the year increased by 50%-54% year-on-year.

CITIC Special Steel (000708) announced that it expects a net profit of 4.13 billion yuan in the first half of the year – 4.23 billion yuan, a year-on-year increase of 50.24%-53.87%.

[Signing a large bill]

Tongkun shares: The Investment Agreement for the Project with an Annual Output of 2 Million Tons of Polyester Fiber was signed, with an investment of about 15 billion yuan.

Tongkun Co., Ltd. (601233) announced that it had signed the Investment Agreement for the Project with an Annual Output of 2 Million Tons of Polyester Fiber with Fuhua Gu Lei and Gulei Economic Development Zone Management Committee. The project plans to requisition about 1,800 mu of planned land for the main factory area (subject to the red line map), so as to form a project with an annual production capacity of 2 million tons of polyester fiber, and build 500 texturing machines and 2,000 looms. The investment amount is about 15 billion yuan (including tax).

Chengdu Luqiao: jointly won the bid for Anning Shuangchuang industrial infrastructure and supporting projects in Yanbian County.

Chengdu Luqiao (002628) Announcement, Company (Leader) — Dalian Municipal Design and Research Institute Co., Ltd. (member) consortium is the survey and design of Anning Shuangchuang Industrial Infrastructure and Supporting Project (Phase I) in Yanbian County — For the general contracting project, the winning bid amount of the project is 0.26% of the construction and installation project fee (the construction and installation project fee is tentatively about 700 million yuan), accounting for about 32.10% of the company’s audited operating income in 2020.

Shengjian environment: winning the bid for the characteristic process research and development and industrialization project of 12-inch CIS integrated circuit: process exhaust system project.

Shengjian Environment (603324) announced that the company received the Notice of Winning the Bid for the Process Exhaust System of the 12-inch CIS Integrated Circuit Characteristic Process R&D and Industrialization Project of Geke Semiconductor (Shanghai) Co., Ltd. issued by Science and Technology Engineering Co., Ltd. of the 11th Design and Research Institute of Information Industry Electronics, and confirmed that the company won the bid, with a total bid price of 79.8 million yuan (including tax).

Innovation in the Straits: Signing 753 million yuan IDC data R&D center project contract.

Straits Innovation (300300) announced that recently, the company and Huitian Technology signed the Construction Contract of IDC Data R&D Center Project in Tongzhou District, Beijing, and reached an agreement on the construction of data center construction projects in buildings 1#, 2# and 18# of IDC(InternetData Center) in Tongzhou District, Beijing, with a contract amount of about 753 million yuan (including tax).

Zhongfutong: Pre-winning the bid of 95.92 million yuan for Guangxi Unicom’s comprehensive maintenance service procurement project.

Zhongfutong (300560) announced that on June 18th, China Mobile Procurement & Bidding Network publicized the bid-winning candidates for Bid Section 5 and Bid Section 6 (the second time) of the open bidding project for comprehensive maintenance service procurement of China Unicom Guangxi Branch from 2021 to 2023, and the company was the bid-winning candidate. The estimated bid amount of the project is 95,923,300 yuan.

[Refinancing]

Jinyun Laser: It is proposed to raise no more than 216 million yuan for IP derivatives operation and promotion projects.

Jinyun Laser (300220) announced that it plans to issue no more than 45.36 million shares to specific targets, and the total amount of funds raised will not exceed 216 million yuan. After deducting relevant issuance expenses, all of them will be used for IP derivatives operation promotion projects.

Kangda New Materials: It is planned to issue convertible bonds to raise no more than 750 million yuan.

Kangda New Materials (002669) announced that the company plans to issue convertible bonds to raise no more than 750 million yuan, and after deducting the issuance expenses, it will invest in "Tangshan Fengnan Kangda Chemical New Materials Co., Ltd. 30,000 tons/year adhesive and upstream and downstream new materials project" and "Fujian Kangda Xinyu New Materials Co., Ltd. 30,000 tons/year adhesive new materials series product project" and supplement liquidity.

Every time the AI news, on February 26th, the market news said that china galaxy and CICC planned to merge through share swap, which is expected to be announced in the next few weeks. In this regard, Xinhua Finance asked the two brokers for verification, and both public relations departments expressed ignorance. The above rumors have been reported many times in 2024, but they were denied by both companies. (Xinhua Finance)

　　CCTV News:On September 28th, Deng Chunping (male, 32 years old, from zhangping city, Fujian Province), who was publicly wanted by the Ministry of Public Security for a class A wanted order, surrendered himself to the public security organs in zhangping city, Fujian Province. Up to now, the Ministry of Public Security issued a Class A wanted order on September 26th, and 10 suspects of mega-telecommunication network fraud have been arrested, all of whom surrendered themselves.

　　It is reported that on March 14, 2015, Li, a native of Youxi County, Fujian Province, received a phone call claiming to be "the person in charge of Youxi County Disabled Persons’ Federation", saying that the Finance Bureau granted him a subsidy of 3,000 yuan for the disabled according to the policy, and Li believed it. Immediately, according to the request of the other party, he took the bank card to operate at the ATM and was cheated of 6,500 yuan. After receiving the alarm, the Public Security Bureau of Youxi County, Fujian Province quickly filed a case for investigation, and successively arrested two suspects, including Wu Mou and Huang, who were responsible for withdrawing money. Following the investigation, the public security organs found that Deng Chunping was the organizer behind Wu Mou and Huang, and the amount involved was as high as 14 million yuan. The criminal suspect Deng Chunping fled for fear of sin, and the public security organs of Fujian Province repeatedly organized the pursuit without success. At about 13: 00 on September 28th, the suspect Deng Chunping surrendered himself to the public security organs in zhangping city, Fujian Province, under the deterrence of the A-class wanted order issued by the Ministry of Public Security and the strong pressure of public opinion.

　　At present, the case is under further investigation. (CCTV reporter Cheng Yi)

　　On September 26, the Ministry of Public Security issued an A-level wanted order (Gong Ji [2016] No.48), publicly wanted 10 fugitives from telecommunication network fraud. Three suspects, Deng Chunping, Huang Yexiong and Deng Zhenchuan, have been arrested. Among the 10 fugitives, 7 are still at large, including Xie Jianhai, Xie Zhian, Chen Fujin, Liao Naijian, Yue Yongfu, Zhihui Wang and Chen Hong.

　　　Xie jianhai, male,Han (HA),1988yearninemoon21suncome outPlace of birth and domicilesite：School Road, Baofeng Village, Shizhong Town, xinluo district City, Longyan City, Fujian Provinceninenumber.ID numberyard：350802198809216010.

　　　Xie zhian, male,Han (HA),1986year10moon10suncome outPlace of birth and domicilesite：Wenzhuang Road, Wenzhuang Village, Shizhong Town, xinluo district City, Longyan City, Fujian Province40number.ID numberyard：35080219861010605X.

　　Chen Fujin, male, Han nationality, was born on July 16, 1979, and his household registration address is No.22, Liquan Village, Sui ‘an Town, Zhangpu County, Fujian Province. ID number: 350623197907160010.

　

　　Liao Naijian, male, Han nationality, was born on March 20th, 1983, and his household registration address is No.108-1, Team 5, xiazhai village, Guming Village Committee, Binzhou Town, Binyang County, Guangxi Zhuang Autonomous Region. ID number: 452123198303201339.

　　Yue Yongfu, male, Han nationality, was born on November 24th, 1974, and his household registration address is No.278-45, Nanhuan 1st Road, Caidu Town, Shangcai County, Henan Province. ID number: 412825197411246437.

　　Zhihui Wang, male, Han nationality, was born on December 6, 1988, and his household registration address is No.29, Xiazhai District 1, yongningzhen, shishi city, Fujian. ID number: 350581198812060538.

　　Chen Hong, female, Han nationality, was born on July 9, 1987, and her household registration address is No.109-6, Team 2, Xijin Village, Xixiangtang District, Nanning, Guangxi Zhuang Autonomous Region. ID number: 452123198707091404.

In the automobile industry, there is a term that is not familiar to the public, but enjoys a high reputation in the professional circle, and that is air suspension. In recent years, air suspension, once regarded as the exclusive configuration of luxury cars, is now accelerating to the mass market.

If we trace back to the development of air suspension, this popular trend has been blowing for several years. More and more star models equipped with air suspension are ready to come out, from /L8/L9 to Weilai, Kelp, and now, the guide price of air suspension has dropped to less than 200,000, further promoting the heat of air suspension.

According to the latest statistics of intelligent driving configuration database of Geshi Automobile Research Institute, from January to December, 2024, the sales volume of new cars with standard air suspension in China was about 816,000, and the penetration rate reached 3.6%. In the same period of 2023, the sales volume of new cars with standard air suspension was 564,000, the penetration rate was 2.7%, and the carrying capacity increased by 44.7% year-on-year. It can be predicted that the development speed of air suspension market will continue to accelerate.

On the one hand, the permeability of air suspension is increasing, and its development speed has exceeded market expectations. At the same time, the supporting price of air suspension is also rapidly sinking, which is close to the standard range of about 200,000 yuan. On the other hand, with the increasing market share of air suspension, the competition between domestic suspension and foreign suspension will become more and more fierce.

The breakthrough of technology, the reduction of cost and the rapid growth of market demand have provided a strong impetus for the popularization of air suspension. Then, will the road of "popularization" of air suspension be smoother and smoother?

The pattern is stable, and domestic substitution is just the time.

Judging from the development in 2024, the market structure of air suspension still continues the characteristics of the rise of domestic forces, and the concentration is getting higher and higher. In 2024, local manufacturers accounted for more than 80% of the air suspension market.

In recent years, the air suspension market has shown a highly concentrated competition pattern, and domestic suppliers have opened a lot of gaps with overseas brands by virtue of technological progress and cost advantages. In 2024, the installed capacity of air suspension market exceeded 800,000 sets, among which Konghui Technology ranked first with 335,470 sets of installed capacity, with a market share of 41.3%. Kong Hui Technology’s market penetration in the field of new energy vehicles is particularly prominent, and its technical advantages enable it to provide customized air suspension solutions for car companies to meet the needs of different models.

Top Group followed closely, with an installed capacity of 209,760 sets and a market share of 25.8%. Top Group occupies an important position in the middle and high-end vehicle market through continuous technological innovation and cost control. Its products are not only comparable to imported brands in performance, but also more competitive in price, which promotes the application of air suspension in more models.

Baolong Technology ranked third with an installed capacity of 159,535 sets, with a market share of 19.6%. Baolong Technology has further consolidated its market position with its own research and development capabilities and customer resources. Its air suspension system is excellent in performance, reliability and cost control, especially in the promotion of low-end market.

In contrast, the market share of traditional international suppliers such as Wayback and Continental Group is 7.8% and 5.0% respectively. As an internationally renowned supplier, Weiback mainly serves high-end brand vehicles, while Continental Group is relatively deep in technology accumulation, but slightly conservative in market competition.

From the overall market point of view, the top five suppliers account for nearly 90% of the market share, and the market concentration is getting higher and higher. These leading enterprises rely on their strong R&D strength and market influence to continuously promote the progress of air suspension technology and market expansion. In the future, with the further maturity of technology and the reduction of cost, air suspension system is expected to be applied in more models, further promoting the growth of market demand.

The rise of domestic brands in the air suspension market is not accidental, and there are many key factors behind it.

From the most intuitive point of view, the development of the new force of building cars has given more opportunities to local air suspension suppliers. For example, Lantu Automobile gave Kong Hui tickets, which verified Kong Hui’s technical accumulation for many years; Ideal helps Kong Hui become a qualified supplier of auto parts. These stories are still vivid, and now the cooperation between new power enterprises and domestic air suspension enterprises is getting closer and closer, and both sides grow together.

In addition, domestic brands have made a significant breakthrough in air suspension technology, which is not only equivalent to imported brands in performance, but also excellent in cost control. In 2023 -2024, domestic air suspension experienced two or three iterations, from single cavity to mainstream dual cavity, which led to great changes in the whole product line and significant cost reduction. This cost advantage enables domestic brands to provide air suspension configurations for more low-end models, thus expanding market share.

"Quick response and supply chain stability are also one of the advantages of domestic air suspension enterprises." Wang Lin (pseudonym), a person in the auto parts industry, pointed out that compared with foreign suppliers, domestic brands have more advantages in development cycle and response speed. The development cycle of foreign suppliers is usually longer, while domestic brands can respond to market demand more quickly and provide flexible solutions. In addition, domestic brands have also performed well in the stability of supply chain and can better cope with market fluctuations.

It is imperative for air suspension to get on the bus on a large scale.

From the whole analysis logic point of view, electrification has greatly changed the load-bearing system of automobiles, and the rapid development of new car-making forces has laid the foundation for the high-end brand of automobiles in China. This also means that the popularity of electric vehicles has brought opportunities for the wide application of air suspension.

The sale of electric vehicles is much more, which makes the air suspension widely used; There are more new forces to build cars, which gives local suppliers more opportunities; Only when the brand of China is high-end can it accommodate the cost of air suspension.

The permeability data of air suspension also illustrates some problems. According to the analysis of intelligent driving configuration data of Geshi Automobile Research Institute, from January to December, 2024, the highest monthly penetration rate of air suspension configuration reached about 4.4%, and the monthly supporting capacity exceeded 100,000 sets, entering an explosive growth stage. The carrying capacity gradually increased from 25,000 sets at the beginning of the year to the peak of 76,000 sets in June and 102,000 sets in December, indicating the steady growth of market demand. At the same time, the permeability started from 1.9% in February and rose in fluctuation, reaching 4.5% in June, indicating that the acceptance of air suspension standard in the market is increasing day by day.

We also see that the development of domestic air suspension enterprises is in full swing. For example, in 2024, Baolong Technology announced the number of designated projects as high as 28, involving an amount of over 11 billion yuan. These projects not only demonstrated the technical strength of Baolong Technology, but also laid the foundation for the large-scale application of air suspension.

A series of indications show that the large-scale popularization of air suspension is close at hand. At one time, air suspension was more common in high-end luxury models, such as, and so on, and its high cost made it difficult to widely promote it. However, with the rise of domestic suppliers, the cost of air suspension is significantly reduced, and the price of vehicles equipped with this configuration is also more close to the people.

Taking 2024 as an example, air suspension has been applied in 200,000-yuan models. It is a typical representative, and the starting price of its model equipped with air suspension is only 289,800 yuan. In addition, the starting price of the latest Krypton 001 is 259,000 yuan, and the air suspension can be optional for the entry model. What is more noteworthy is that the dark blue G318 is equipped with an air suspension version, and the starting price is only 199,900 yuan.

"At present, there is an obvious sinking trend of air suspension on new energy vehicles, and it is likely to further drop to 180,000-190,000 in the future." Wang Lin believes that the standard value of air suspension will be lowered, and the possibility of getting on the bus on a large scale is very high.

However, Wang Lin also added his own analysis. From the aspects of quality, design process and overall cost (including maintenance cost), there is limited room for the cost of air suspension to sink further. From the perspective of cost analysis, he pointed out that it is difficult to reduce the cost of even a single-cavity air spring, because the whole air suspension system includes the body and the supply system, such as air pump, air valve, compressor, gas storage tank and sound insulation layer. The development cost of the system has dropped from about 2000 yuan before to about 1800 yuan at present. Unless domestic manufacturers make breakthroughs in core components, it is unlikely that the cost will be further reduced.

In the future, with the further development of technology and the continuous reduction of cost, air suspension is expected to be applied in more models. Therefore, it is predicted in the industry that the overall permeability of air suspension will reach about 15% in 2025. With the development of intelligent suspension technology, air suspension will be combined with more intelligent driving functions to provide consumers with more intelligent and personalized driving experience.

What is the odds of air suspension going out to sea?

When the domestic air suspension market structure is relatively stable, the competition is becoming more and more fierce. Therefore, we have also seen a new trend. With the maturity of domestic air suspension technology and the improvement of market competitiveness, domestic suppliers have begun to look to the international market.

Recently, Baolong Technology received the Notice of Fixed Point from a famous European automobile company, and became a component supplier for its brand-new platform project, Air Supply Unit (ASU) of air suspension system. The life cycle of the project is 7 years, and the total amount exceeds RMB 160 million. It is expected to start mass production in 2027. This indicates that the domestic air suspension technology has been recognized by the international market, laying a foundation for the further expansion of domestic suppliers in the international market.

However, we also need to see the challenge of domestic air suspension forces going out to sea. Judging from the overall market structure, foreign air suspension forces are not in a strong position in the China market. For example, although Kangdi has built a factory in Jiangsu to promote localization, its speed is slow; Weiback, on the other hand, relies entirely on imports and has not yet set up a factory in China. However, they are in a strong position in the international market.

In the international market, the field of air suspension has long been monopolized by a few foreign giants. Condi (affiliated to Continental Group) and Weiback are two giants in the global market, and they have absolute advantages in technology and market share. Japanese manufacturers also mainly rely on the products of Condi and Weiback in the luxury car field, and almost no domestic products are used.

Domestic air suspension enterprises also clearly realize that the road to sea is not smooth sailing. As Chao Wang, general manager of Baolong Science and Technology Supply Chain Development Center, said, when China enterprises enter the international market, they are often restricted by many factors. Whether an enterprise can win a project order depends not only on whether the product is excellent and whether the price is competitive, but also on many other complex factors that may affect the cost control, delivery ability and cooperation experience with customers.

Wang Chao also added, "Maybe after we go, we can still build a certain advantage through a period of adaptation, but this advantage may not be so obvious compared with our advantage in China."

To this end, Baolong Technology needs to solve the possible challenges from the perspective of supply chain. In 2024, Baolong Technology established a new department supply chain development center. In addition to optimizing the procurement strategy, another important task of the new department is to strengthen the overseas supply chain.

In fact, Baolong Technology started earlier in overseas layout, and had previously set up some factories overseas. Today, Baolong plans to build more purely overseas supply chains. Chao Wang said that although Baolong had some overseas factories before, the original supply chain was still dominated by China supply chain. Now, due to geopolitical problems, many customers demand the localization of supply chain, so the new department will help overseas factories to establish a purely overseas supply chain.

However, in his view, compared with foreign-funded enterprises, China enterprises still have a comparative advantage. "For example, in terms of efficiency, if a China supplier can complete a project in six months at home, a foreign investor in China will complete it in nine to twelve months, and if it goes to Europe, a China supplier may complete it in nine months, and a foreign investor may complete it in 12 to fifteen months. This step difference also exists. Of course, this data description is not for specific projects, but mainly for an image description. "

Despite the challenges, Chao Wang is full of confidence in the future development. He believes that in the next few years, China suppliers will gradually catch up. "Generally speaking, China suppliers will be able to provide products with advanced technology, good quality and competitive cost in the future."

With the continuous progress of technology and the further reduction of cost, domestic suppliers are expected to occupy a more important share in the international market and contribute more to the global development of air suspension.

Gai Shi Xiao Ji

Air suspension is moving from high-end to mass, which is driven by many factors, such as technological breakthrough, cost reduction, market demand growth and the rise of domestic suppliers.

With strong R&D strength and cost advantage, domestic suppliers have gained significant market share in the domestic market and started to expand into the international market. With the further development of technology and the continuous expansion of the market, air suspension is expected to become the choice of more ordinary consumers and inject new impetus into the intelligent and comfortable development of the automobile industry.

Perhaps, in the near future, air suspension will not only become the standard in the domestic automobile market, but also occupy an important position in the global market.