Cyber hackers, who committed crimes in groups, were sentenced for making and spreading obscene articles on the Internet for profit, and committed crimes again during probation. These are the characteristics of the cases involving Li and Chen in Lishui, Zhejiang Province, among the six cases of trafficking in pornography publicly notified by the National Office for Combating Pornography today. In fact, judging from the facts of the six cases, each case is shocking in terms of both the means of committing crimes and the degree of harm.

　　The person in charge of the national office of "eliminating pornography and illegal publications" pointed out that these six cases are typical cases in which the national office of "eliminating pornography and illegal publications" chose "net" and "protecting seedlings" to investigate and deal with important progress, which has been completed or the investigation has ended.

　　Rent an overseas server to commit crimes in groups.

　　The first case reported by the national office of "eliminating pornography and illegal publications" was a case in which Li and Chen in Lishui, Zhejiang Province made and disseminated obscene articles for profit.

　　According to reports, in November 2018, according to the report of the masses, the Economic Development Zone Branch of Lishui Public Security Bureau filed a case to investigate the case and set up a task force. At present, the case has been ascertained, and eight suspects have been arrested, including Li and Chen, the principals who directed and produced obscene videos. At the same time, more than 100,000 obscene videos were seized, and the amount involved was more than 7 million yuan.

　　According to the national office of "eliminating pornography and illegal publications", from 2016 to 2017, Li and Chen Moumou filmed obscene videos for sale in the name of "Kuramoto C, underwear brother, and 91 principal". Since October 2017, Li and Chen, Chen Mou, Lin and others have rented overseas servers and set up 91B1 obscene websites to make profits by selling members and recharging VIP. Zhao, Zhu and others filmed obscene videos and uploaded them to the network disk, and then sold them through the 91B1 website. In this case, more than 100,000 people were purchased, distributed in various places and overseas areas. At the end of 2018, the task force successively arrested four principals, including Li and Chen, in Guangdong and Hebei. Recently, the task force captured four people, including Zhao and Zhu, in Shandong, Hunan and Guangxi.

　　The national office of "eliminating pornography and illegal publications" said that the suspect in this case has a high reputation on the Internet. In 2016, the criminal suspect Zhao became a "great god" by making and selling his own obscene videos on the Internet in the name of "91 Daige", and his videos were found on almost all Chinese obscene websites.

　　Not only that, the main suspect Li is a hacker and was sentenced for hacking cases; Zhao was sentenced for making and spreading obscene articles on the Internet for profit, and is still on probation. "Different from previous cases, the suspects who filmed obscene videos in this case did not fight alone, but committed crimes in groups." The National Office of "Combating Pornography and Illegal Publications" pointed out that in 91B1 website, there are as many as 20 suspects who are engaged in making obscene videos for profit, including a female criminal suspect in Taiwan Province.

　　26 people who imitated Tik Tok to sell pornography were detained.

　　26 people were criminally detained and 110,000 obscene short videos were seized. Today, the National Office of "Combating Pornography and Illegal Publications" reported the case of "Fast Fairy" short video App spreading obscene articles for profit in Shenzhen, Guangdong Province, saying that the short video platform involving pornography in this case was huge.

　　The National Office for Combating Pornography said that in this case, the "Fast Fairy" App claimed to be an "adult version of Tik Tok". Since it was launched in October 2018, its pages and browsing methods have all imitated "Tik Tok", but only obscene and pornographic short videos have been disseminated.

　　To make matters worse, operators have also introduced incentives. As of the time of the incident, there are nearly 3 million registered users, and more than 1,000 users have uploaded obscene videos. Operating gangs have made a profit of over 10 million yuan by charging gambling sites advertising fees.

　　The national office of "eliminating pornography and illegal publications" said that on March 23 this year, Longgang police began to collect nets in 15 cities across the country and arrested 26 suspects. At present, the App has been seized according to law, and the case is still being further explored.

　　50,000 cross-border agent development members

　　Judging from the situation reported by the national office of "eliminating pornography and illegal publications", the case of "June 29" spreading obscene articles for profit in Guigang, Guangxi was also extremely bad.

　　"In June 2018, the public security organs of Guigang City inspected and found that a netizen in the jurisdiction was suspected of spreading obscene video clues and filed a case for investigation." According to reports, this netizen is the general agent and customer service of "Pymai" obscene video website.

　　The National Office for Combating Pornography pointed out that this website management team has a clear division of labor and a strict organization. The gang has more than 10 main members and more than 100 offline agents, involving 20 provinces and countries such as Malaysia and Singapore. Through the combination of website and WeChat group, the gang has developed more than 50,000 members, involving more than 13 million yuan. At the end of 2018, the task force launched a unified arrest operation, arresting 16 suspects one after another, and 14 people including Jia Mou were arrested according to law, detaining more than 50,000 pornographic videos stored in the server, and destroying 3 studios used to disseminate obscene pornographic information. In February this year, this case was transferred to the procuratorate for review and prosecution.

　　Hundreds of female anchors engage in obscene performances.

　　In the case of Shanghai Changning "Cherry Live" App spreading obscene articles, the public security organs found that hundreds of female anchors were engaged in obscene performances.

　　According to the introduction of the National Office for Combating Pornography, in January 2019, the network inspection of Changning Branch of Shanghai Public Security Bureau found that there were some pornographic Apps in Apple’s mobile App store, among which the "Cherry Live" app was the most popular. Finally, it was verified that there were hundreds of female anchors engaged in obscene performances and spreading obscene videos in this App, with tens of thousands of viewers and millions of funds involved.

　　After a lot of work such as preliminary investigation and fixed evidence, the task force of Changning Public Security Bureau went to Chongqing, Hunan, Guangdong and other places to arrest. At present, 43 people involved in the case have been successfully arrested, all of whom have been criminally detained, and the case is under further investigation.

　　The server develops 3000 members abroad.

　　According to the national "anti-vice and pornography" office, in August 2018, the public security organs of Lu’ an City, Anhui Province found in their work that the website named "Zhengtai Community" disseminated obscene videos and pictures.

　　After further investigation, it was verified that this website was founded by Qi, with a server abroad and more than 3,000 registered members. There are more than 2,000 obscene videos and more than 8,000 pictures on the website, some of which involve minors. The public security organs arrested three suspects, including Qi. In March 2019, the case was prosecuted by the procuratorate.

　　"cute girl" spreads child pornography videos

　　The profit-making case of spreading child pornography videos in the "Mengmeizi" forum in Liaocheng, Shandong Province is the sixth case notified by the National Office for Combating Pornography and Illegal Publications.

　　"In August 2018, according to the national ‘ Eradicate pornography and illegal publications ’ The office turned to clues, and the public security organs of Liaocheng City and yanggu county City quickly carried out investigations, cracked the case and arrested the main suspect Liu. " The National Office for Combating Pornography said that since July 2017, Liu rented an overseas server through a network technology company in Lianyungang, Jiangsu Province, and established a "cute girl" forum to sell and disseminate child pornography videos, with a total of more than 130,000 members, including more than 400 paid members, with a profit of more than 70,000 yuan. At present, this case has been handed over to the procuratorate for review and prosecution.

　　Obscene and pornographic information is the focus of the crackdown

　　The person in charge of the national office of "eliminating pornography and illegal publications" pointed out that obscene pornographic information is the focus of the current crackdown. In the first quarter of this year, the "anti-pornography and illegal publications" department strictly rectified the dissemination of obscene and pornographic information by using live webcasts, short videos, "two micro-ends" and other platforms, and resolutely investigated and dealt with a large number of cases of online pornography, pornography and pornography.

　　The person in charge said that since the beginning of this year, the departments of "eliminating pornography and illegal publications" in various places have taken the initiative to maintain the high-pressure situation of cracking down on illegal and criminal activities involving pornography, and promoted the in-depth development of special actions such as "net work" and "protecting seedlings" through investigating cases. Among them, from January to March, a total of 1,079 cases of "cracking down on pornography and illegal publications" were filed nationwide, including more than 130 criminal cases and 541 cases involving the Internet.

　　Legal Network Beijing April 18 th

Original title:Hard enough, not only a new milestone in China’s science fiction movies.— — A Brief Comment on Wandering Earth 2, a New Year movie.

Wen Zhen Cheng Bo (Professor, Doctoral Supervisor and Vice President of Shanghai Film Academy, Shanghai University)

New film viewpoint

Special fund support for the development of national film industry

How does the prequel become a sequel?The experience of a series of films tells us that each film should be a new "this one", not just a predecessor or sequel to a certain film, and should not be the so-called "second life, second life and third life" rhythm.

Why can science fiction be hard-core?Characters and stories must first stand up; Then the audio-visual realism and spectacle should be enough, and it is better if we can use new technologies and platforms; Furthermore, whether we can leap from "fantasy" to "thought", the discussion on ideology and philosophy lies in audio-visual and stories, but it is not closed, which can inspire questioning and reflection.

If we say that the "window opening" and "ceiling" of China’s sci-fi movies in 2019 have been going around for a few years, and the film market has changed due to the epidemic, it is difficult for domestic sci-fi movies to produce any hardcore masterpieces. By the Spring Festival in 2023, Wandering Earth 2, the second part of this series of movies, tells the story of The Wandering Earth’s prequel, but it has "broken the door" beyond the hardcore level of its predecessor.

Storytelling, Wandering Earth 2 shows how The Wandering Earth’s basic world outlook structure came into being, and two crises before Jupiter crisis — — The attack in 2044 and the moon crisis in 2058.

This is a step in the process from the present to the future, and it is a phased state from the near future to the farther. The "Wandering Earth" project is a grand human epic spanning 2,500 years. How it happened and how it was possible, and the credibility logic needs to be shown by movies.

On the surface, the crisis in 2044 is how the mainstream "Wandering Earth" faction responded to the "terrorist attack" of the opposition "Digital Life" faction. This is a routine of spy war and thrilling action movies, but at the same time, it has completed the personal construction of Liu Peiqiang and Han Duoduo (The Wandering Earth’s grandfather named his sister Han Duoduo to commemorate his daughter who died of illness), and the "space elevator" for those who face the wall in "Three-body".

At the same time, the appearance of Tu Hengyu leads to the clue of supercomputer artificial intelligence 550W. The mirror reverse writing "MOSS" not only appeared in Liu Cixin’s Supernova Age and China 2185, but also produced intertextuality with the supercomputer of the world’s classic sci-fi movies in some details, such as "Roaming in Space in 2001" and "Alpha City". When the red eye or camera of the supercomputer flashes, there will be a faint prompt sound.

The idea of reverse writing in the mirror of 550W may also be influenced by the classic mirror that says "redrum" and "murder" in reverse. The dual nature of artificial intelligence represented by 550W may be the underlying cause of the two crises. This is a technical ethics issue, a philosophical issue, and even a future realistic issue.

The "Moon Crisis" is the core plot of Wandering Earth 2. If Liu Peiqiang’s clue is the "real universe" directly traced forward, then Tu Hengyu can be said to be a "meta-universe" clue. The virtual reality and life and death were originally antagonistic and either-or, just like the crisis in 2044, but in the face of the crisis of all mankind, people from different countries can unite if they need it, because "there is no human civilization.

The nuclear bomb is used to destroy the moon, which is unity and trust in one dimension, but the key can’t be unlocked, which is division and suspicion in a higher dimension. Only with greater human sacrifice, hands-on operation will have the meaning of unity. Similarly, can the virtual and the real be United? The initial heart of Liu Peiqiang in the real world and Tu Hengyu in the virtual world is "ego", and the responsibility and kindness in human nature become the final choice.

This is not individual heroism, it is "human" collectivity and people’s nature.

Just as Tu Heng-yu’s crossing between the virtual and the real is like "Interstellar" passing through a black hole, he has become a higher-dimensional self, which can send back information to remind human beings of the crisis. In the choice between angels and demons, the continuation of nature is his own god. In this sense, should the community of human destiny include the unity of reality and falsehood, and can it transcend life and death in the process of drawing a blueprint like a foolish man moving mountains in 2500 years? The answer seems to be yes.

Wandering Earth 2 further interprets and deepens the theme, the so-called "Chinese scheme", in the openness of absorbing the nutrition of world science fiction movies. In the sci-fi coalition government, which is almost the same as the real United Nations, the emaciated "Miss Zhou" wearing a Chinese tunic suit with a national flag tells the story of the first healed thigh bone.

Yes, this character’s surname is Zhou. He can evoke Chinese’s collective memory. He can also make a decisive decision based on the belief that "our people are fine" in the face of tidal danger and surveillance cameras. This "last-minute rescue" routine seems to be a familiar way for us.

Wandering Earth 2 clearly shows that the industrial production level of China’s films has reached a new height. The special effects shots are real and full of details, and they dare to show them to the audience frankly, with no intention of concealing or hiding others.

The hardcore degree of paragraphs such as "Space Elevator", "Nuclear Explosion on the Moon", "Returning to Shanghai", "Diving to Restart the Internet Root", "Starting from the Space Station Warrior" and "Stupid Robot Dog" are not inferior in the history and forefront of the world science fiction movie history.

In the combination of narrative and special effects, the structure and rhythm of the so-called emotional drama and hardcore drama are not perfect, but they are basically compact and effective. Moreover, there are only two films in this series at present, and there should be a third film in the future, such as "Helium Flash Crisis in the Sun". If this is the case, the "Wandering Earth" series will show that China’s ability to incubate its own series of films from contemporary IP has reached a new and even global level, and it will also "go global" in the combination of creativity and craftsmanship, in the exploration and interpretation of the theme, and in China’s films.

In this sense, the hardcore of Wandering Earth 2 is not only in the field of science fiction movies, but also a new milestone of science fiction movies in China.

　　Apart from being a singer, Jay Chou is also an out-and-out e-sports fan. In April this year, Jay Chou and IDG co-founded the "Magic Jie E-sports" brand, and the first e-sports Internet cafe jointly opened by the two parties officially settled in Shenzhen.

　　The overall specification of this internet cafe is completely against the standard of high-end internet cafes, and the price is also the standard of high-end internet cafes. Some netizens visited the first Jay Chou Internet cafe in Shenzhen, and it was not cheap in terms of price. The price of the lobby was 10 yuan/hour, while the most expensive VIP seat reached 300 yuan/hour.

　　Different from other Internet cafes, the display screen, mouse, keyboard and headphones of Jay Chou Internet Cafe are all customized versions with Jay logo, and the host is a high-end game console known for its powerful game performance and high price.

　　The following private room is Jay’s exclusive private room, which is a complete copy of Jay Chou’s office in Taipei. Besides playing games, you can also enjoy the office in Jay Chou.

Compilation Shu Wang Cong

Editor: Wang Duoyu

Typesetting Shu Shui Chengwen

The long-term vision for artificial intelligence (AI) is to develop AI systems that can make major scientific discoveries, learn autonomously, and acquire knowledge autonomously.

虽然“AI 科学家”（AI scientist）这一概念还只是一种理想化的愿景，但基于智能体（agent）的AI技术的发展，为开发能够进行对话、具备反思学习和推理能力的AI智能体（AI agent）铺平了道路，这些AI智能体能够协调大型语言模型（LLM）、机器学习（ML）工具、实验平台，甚至是它们的组合。

近日，哈佛大学医学院 Marinka Zitnik实验室（高尚华博士为第一作者）在 Cell 期刊发表了题为：Empowering biomedical discovery with AI agents 的文章，系统介绍了利用 AI 智能体（AI agent）推动生物医学发现。

该文章提出了这样一个观点——“AI 科学家”可以被由人类、大语言模型、机器学习模型及其他工具（例如实验平台）组成的复合AI系统所支持的 AI 智能体（AI agent）所实现。

我们将“AI 科学家”设想为具备批判性学习和推理能力的系统，它们能够通过协作智能体整合 AI 模型和生物医学工具，并与实验平台相结合，从而为生物医学研究提供助力。

生物医学 AI 智能体不是将人类排除在发现过程之外，而是将人类的创造力和专业知识与 AI 分析大量数据、探索假设空间和执行重复性任务的能力相结合。AI 智能体将能够熟练完成各种任务，规划发现工作流程并进行自我评估，以识别并解决其知识中的差距。这些智能体使用大语言模型（LLM）和生成式模型来实现结构化记忆以进行持续学习，并使用机器学习工具将科学知识、生物学原理和理论融入其中。AI 智能体可以影响从虚拟细胞模拟、可编程的表型控制到细胞回路设计以及开发新疗法等各个领域。

The first author, Dr. Gao Shanghua, received his doctorate from Nankai University and is now a postdoctoral researcher at Harvard Medical School

The complexity of biology requires the flexibility to break down complex problems into executable tasks. AI agents can break down problems into manageable sub-tasks, which are then solved by AI agents with specific functions and integrate scientific knowledge. In the near future, AI agents can accelerate the discovery process by making workflows faster and more resource-efficient.

Leveraging AI agents to advance biomedical research

The continuous development and application of data-driven models

AI agents in the biomedical field – from LLM-based AI agents to multi-agent systems that integrate AI models, tools, and physical devices

Level of autonomy of AI agents

Cases of autonomy levels for AI agents in genetics, cell biology, and chemical biology

Core terms of machine learning

Key modules in AI agents: perception, interaction, reasoning, and memory modules

Components of a biomedical AI agent

The challenges of AI agents in biomedical discovery

AI agents can improve the efficiency of routine tasks, automate repetitive processes, and analyze large datasets to outperform current human-driven efforts in scale and accuracy. This automation allows for continuous, high-throughput research that human researchers cannot conduct individually at the same scale or speed.

Looking to the future, AI agents can provide insights beyond what traditional machine learning can achieve by making predictions across temporal and spatial scales before obtaining experimental measurements at both temporal and spatial scales. Ultimately, AI agents may help uncover new patterns of behavior in biological systems.

Original link:

https://www.cell.com/cell/fulltext/S0092-8674 (24) 01070-5

Read the original text

　　CCTV News:Every winter and spring is a high incidence of influenza. Recently, the National Influenza Center released the influenza surveillance report for the second week of 2019. The report shows that the level of influenza activity in the northern and southern provinces of China continues to rise, and it has reached the peak level of influenza epidemic. The flu is fierce, but some misunderstandings about the flu may be more terrible than the flu itself!

　　Myth 1: This year’s flu is more serious than in previous years.

　　Feng Zijian, deputy director of China CDC, said that the overall epidemic intensity of influenza this year is not as strong as last year, but it may be slightly stronger in some local areas. According to past experience, influenza may reach its peak in a week or two, and then the activity intensity of influenza will fall back.

　　% of influenza-like cases reported by sentinel hospitals in southern provinces in 2015-2019 Source: National Influenza Center.

　　According to the report released by the National Influenza Center, in the second week of 2019, the ILI% reported by sentinel hospitals in southern provinces was 5.5%, which was higher than the same period in 2016 and 2017 (3.2% and 3.1%) and lower than the same period in 2018 (6.0%); The ILI% reported by sentinel hospitals in northern provinces was 5.3%, which was higher than that in 2016 and 2017 (3.2% and 3.6%) and lower than that in 2018 (5.5%).

　　Song Tie, deputy director of the Guangdong Provincial Center for Disease Control and Prevention, said that there were more outbreaks of influenza in primary schools this year, but with the school holidays, this outbreak will gradually decrease.

　　Myth 2: This year, the emergence of "EB flu" and other variants of influenza virus is even more harmful.

　　Recently, a message about the so-called "EB flu" circulated in the circle of friends, saying that "EB virus caused a severe flu", and the news that "the flu virus turned to attack children’s brains this year" also made many people fidget. Is there a mutation in this year’s influenza virus, and is it more harmful than before? Experts said that at present, the variation of influenza virus has not been found in various places, and there is no EB flu in medicine.

　　Weibo screenshot

　　According to experts, although there is EB virus, there is no EB flu. Symptoms such as fever and sore throat caused by EB virus have nothing to do with influenza, and EB virus itself is not highly pathogenic and contagious, so it generally does not need special treatment.

　　Myth 3: Influenza is treated as a common cold.

　　The symptoms of the common cold are mild, and most of them are respiratory symptoms such as sore throat, cough and stuffy nose. Generally, they will get better after seven to ten days. If there are complications, they are usually sinusitis and otitis media, and the consequences are not serious; The flu will be accompanied by high fever above 38℃, chills, dizziness, headache, muscle aches, etc., and it will also be complicated with severe pneumonia and myocarditis, which is sometimes fatal and highly contagious. Hundreds of thousands of people worldwide die of the flu every year. Experts suggest that once you have cold symptoms, you should go to the hospital in time to check and diagnose whether it is the flu or not, and prescribe the right medicine.

　　Myth 4: taking drugs "just a few days"

　　Experts pointed out that the antiviral drug oseltamivir can alleviate flu symptoms and reduce complications. However, oseltamivir has its timing: use it within 48 hours after suffering from influenza, and the earlier the effect, the better. If it exceeds the time limit, the effect will be ignored.

　　Other cold medicines are only "symptomatic medicines" to relieve symptoms, and any cold symptoms can only be eliminated through the resistance of patients’ own immunity.

　　Zheng Rongxiu, the chief physician of the General Hospital of Tianjin Medical University, pointed out that there are many anti-cold drugs now, which just make the symptoms of cold less and make people feel better, but have no effect on the course of the disease itself. After the course of the disease, most patients can recover with our immunity.

　　Myth # 5: When you have the flu, the infusion will get better quickly.

　　According to experts, glucose, saline, antibiotics or traditional Chinese medicine injections are generally infused, and none of them are necessary for treating influenza. Glucose and salt can be ingested from the diet, so as long as they can eat, there is no need to directly enter the vein. Influenza is caused by virus, and antibiotics are used to kill bacteria, which has no effect on virus infection and can’t prevent secondary bacterial infection. If you have a bacterial infection, you need to use antibiotics or take them orally. There is no need for infusion. As for traditional Chinese medicine injections, at present, the side effects are unknown and the infusion risk is high.

　　No matter from the perspective of saving medical costs or safety, we should follow the principle that drugs can be taken orally without injection, and drugs can be injected without infusion.

　　Myth # 6: Mixed use of multiple drugs is effective.

　　Experts emphasize that taking a variety of cold medicines will not play much role in the curative effect, on the contrary, the risk of adverse reactions will be doubled.

　　Xie Lixin, director of the Department of Respiratory Medicine, the First Medical Center of the PLA General Hospital, said that it is a three-point poison. In clinical work, the related side effects caused by drug abuse or excessive overdose are not uncommon, and the lessons are very profound.

　　Myth 7: relying on "remedies" such as vinegar fumigation to prevent influenza

　

　　In order to prevent the flu, some people smoke vinegar at home. Experts say that acetic acid can only kill bacteria when it reaches a certain concentration. Moreover, the flu virus is not a bacterium, and it cannot be killed by acetic acid at all. Blind vinegar fumigation will also aggravate the condition of patients with bronchitis and emphysema.

　　Others rely on oral vitamin C to prevent influenza. Experts say that taking enough fruits and vegetables has the same effect as oral vitamin C, which can improve immunity, but it has no antiviral effect. According to the method of drinking Radix Isatidis and other traditional Chinese medicines to prevent influenza, experts said that Radix Isatidis is cool and not beneficial to all patients.

　　Yang Shuyu, president of Xiamen Medical Association, Fujian Province, pointed out that it is very important to pay attention to improving one’s immunity when a cold is prevalent, and blindly taking drugs will affect and damage one’s immunity.

　　Myth # 8: Strong people don’t have to be afraid of the flu.

　　Experts say that people who are strong and have strong resistance should not think that their chances of getting the flu are low, so they don’t pay attention to rest and prevention, so that the virus also has the opportunity to take advantage of it, such as fatigue, hunger, or soaking clothes after sweating a lot. Among influenza complications, the incidence of myocarditis is higher in healthy young adults. This is because these people are more immune, and when they are invaded by the virus, their own defense system will also damage myocardial cells while removing the virus.　

　　The prevention methods of influenza in active period have long been known.

　　Do a good job in preventing influenza:

　　1, keep indoor air circulation, pay attention to the clean environment;

　　2. Maintain adequate sleep, healthy diet and moderate exercise;

　　3. Pay attention to the weather change, add or subtract clothes with the temperature change to avoid catching cold;

　　4. Pay attention to personal hygiene, change clothes and wash hands frequently, and cover your mouth and nose with paper towels or sleeves when sneezing or coughing.

　　Children and the elderly should pay special attention to:

　　1. Put an end to letting children attend classes with illness, try to avoid contact with patients with influenza-like cases, and wear masks if necessary;

　　2. It is suggested that the elderly and residents with basic diseases should be vaccinated as soon as possible before the peak of influenza;

　　3, the school nursery institutions should do a good job of absence monitoring due to illness and morning and afternoon inspection.

　

　　Source: Weibo, Beijing Center for Disease Control and Prevention.

　　China News ServiceBeijing, July 14th (Reporter Gao Kai) According to the real-time data of Lighthouse Professional Edition, as of July 14th, the box office (including pre-sales) of China mainland movies in 2023 exceeded 30 billion yuan (RMB, the same below), which was close to the total box office of 30.067 billion yuan in 2022.

　　According to the data of Lighthouse Professional Edition, up to now, the top five films at the box office in 2023 are: Man Jiang Hong (4.544 billion yuan), The Wandering Earth (4.029 billion yuan), Disappeared She (3.263 billion yuan), Bear with Me (1.495 billion yuan) and Octagon.

　　In addition, Unfamiliar Road of Life, Speed and Passion 10, Unknown, Deep Sea and King of the Sky rank six to ten respectively.

　　Since the Spring Festival this year, the domestic film market has shown a rapid recovery trend, and the box office performance of domestic films is particularly prominent. At present, among the top ten films at the box office, domestic films occupy nine of them and occupy the top five seats, which fully shows their dominant position in the cinemas in China.

　　Since entering the summer file, domestic films such as Disappeared She, In an Octagonal Cage and Three Wan Li in Chang ‘an have continuously triggered a movie-watching craze here. The data shows that as of the 14th, the box office of this summer file has exceeded 7.8 billion yuan.

　　On this basis, in late July, a number of films with box office appeal will be released soon, and the summer file is considered to be very likely to have further bright performance.

　　Among them, the comedy "Super Family" produced by Mahua FunAge announced the final file on July 21. As of press time, the number of people who want to see the film in the lighthouse professional edition has exceeded 860,000; Directed by Dapeng and starring Bo Huang and YiBo, the drama "Enthusiasm" is scheduled for July 28th. At present, the number of people who want to see it has reached 610,000. In addition, the huge fantasy costume blockbuster "Feng Shen I" was finalized on July 20, which attracted people’s attention with its all-star cast, mysterious scenes and adaptation of the story of "Feng Shen Romance". At present, the number of people who want to see the index has reached nearly 470,000.

　　The industry believes that the monthly box office in July 2023 is expected to break through the 7 billion yuan mark, creating a new box office record in the same month in China’s film history.

　　The Spring Festival is approaching, and the population is flowing in large numbers, so the number of people who work in cities and return home to visit relatives for holidays will increase rapidly. This has also brought severe challenges to the treatment of rural COVID-19.

　　"Grassroots medical and health institutions have undertaken a large number of tasks of first diagnosis of patients and classified management of key populations." On January 14th, Nie Chunlei, director of the Department of Primary Health and Health in National Health Commission, said that there was an imbalance in medical resources between urban and rural areas, with obvious differences, and health service resources in rural areas were relatively insufficient. "Grassroots village doctors urgently need to master the knowledge and skills of Covid-19 infection diagnosis, severe early warning and treatment, especially the use of antibiotics, hormones and small molecule drugs, so that patients can be effectively treated."

　　On January 11th, the General Practice Branch of Chinese Medical Association, together with several branches, issued the "Guidelines for Diagnosis, Treatment and Service of Infections in novel coronavirus (First Edition)" (hereinafter referred to as the "Guidelines"), which elaborated on diagnosis, clinical classification, identification, treatment and treatment of severe cases.

　　How to warn of moderate and severe diseases?

　　"For the grassroots, the evaluation of COVID-19’s diagnosis and clinical typing is more important, and it is also the whole of the diagnosis and treatment strategy." Wu Hao, the correspondent of the Guide and dean of the School of General Practice and Continuing Education of Capital Medical University, said.

　　In the evaluation of patients’ clinical typing, Wu Hao said that the majority of grassroots village doctors need to pay special attention, and the evaluation of vital signs can be carried out through a simple "four-piece set" of body temperature, respiration, heart rate and blood pressure; In the measurement of finger oxygen saturation, due to the low outdoor temperature in winter, the village doctor found that the patient’s limbs or skin were cold, and its oxygen saturation value may be less than 93%, but this does not mean that the patient is at risk, and it is necessary to judge by observing whether the lips are purple and dry.

　　Imaging examination can be based on chest X-ray or CT. If there is pneumonia in COVID-19, most of it occurs in the lower lungs. If there is no CT in rural medical institutions, you can auscultate whether the patient’s lower lungs are accompanied by wet rales (if there is, CT examination is not necessary); Instead of taking X-ray chest film, you need to pay attention to the patient’s posterior and anterior and lateral films, and sometimes you can see some exudative and inflammatory lesions. Although the X-ray chest film may miss the diagnosis, if the chest film shows pneumonia, the actual situation of the patient will be more serious.

　　"What needs to be repeatedly emphasized is the early warning of severe illness." Wu Hao said that the patient’s three situations indicate that it is very dangerous and may progress to severe illness. First, moderate and severe dyspnea occurred, including (meeting one of the following conditions) heart rate greater than 120 beats/min, breathing frequency greater than 30 beats/min, and breathing with an auxiliary ventilator (pay attention if the patient cannot speak a whole sentence during the consultation); Second, the oxygen saturation is lower than 93%; In addition, if the patient has chest pain, falls, changes of consciousness, low blood pressure, decreased urine output, severe vomiting or diarrhea, etc., we should also consider severe warning.

　　Zhang Wenhong, director of the Department of Infectious Diseases of Huashan Hospital affiliated to Fudan University, said during the training that after the implementation of the "Class B and Class B Management" policy, it is crucial for grassroots doctors to master the transformation from Chinese diseases to severe diseases in the process of normalizing COVID-19 treatment. In particular, the clinical classification of patients was adjusted in the "novel coronavirus Infection Diagnosis and Treatment Program (Trial Tenth Edition)", instead of ordinary type, it was medium. "Light and medium-sized should be treated at the grassroots level. Therefore, the grassroots should prevent medium-sized to heavy-duty, and heavy patients need to be referred in time. "

　　Zhang Wenhong said that in the clinical early warning of severe illness, one indicator has changed and it is necessary to be alert to the deterioration of the patient’s condition, that is, the patient is "hypoxic after activity; After slight activity, the oxygen saturation value is less than 94%, which can make the patient walk back and forth in the corridor. If his CRP(C-reactive protein), lactic acid and other indicators are normal, it means that the oxygen saturation value has decreased, which is also a signal of the progress of the disease.

　　How to use hormones and antibiotics?

　　Is it really effective for rural doctors to use the four-piece set of "antiviral+antibiotic+hormone+antipyretic"?

　　Wu Hao explained that, in fact, the elderly people in rural areas were not treated in time after onset, and there was malnutrition. When he went to the clinic for medical treatment, he might be in the acute pneumonia period, and even had a bacterial infection. At this time, the village doctor will give hormone and antibiotic treatment, and the effect will be more obvious.

　　Regarding whether antiviral drugs can be used for more than 7 days, Wu Hao said that the time of viremia is usually 7 days. The reason why antiviral drugs are prescribed to be used within 5 days of onset is because the earlier they are used, the greater the benefit, which also takes into account the incubation period of 1 ~ 2 days. "For the elderly and frail patients, the process of virus clearance is slow. At this time, even if the illness lasts for more than 7 days, it will still be effective to continue using antiviral drugs."

　　Wu Hao further said that the use of antibiotics should also avoid blindness and should be judged with reference to the patient’s indications. For example, if the patient coughs dry or coughs white sputum, or has less sputum in the early stage, this is a viral infection; If the patient has pus or coughs yellow sputum, it is generally a bacterial infection. If the village doctor doesn’t have the above-mentioned accurate detection means, he can write it all in combination with the patient’s situation, that is, his family members are infected and have flu symptoms, and he also has lung symptoms, which is definitely viral pneumonia, but if his family members don’t have it, it is the possibility of community-acquired pneumonia.

　　In order to facilitate the operation of primary doctors, the "Simplified Edition" published on January 4th referred to the "four-step" treatment of COVID-19 at the primary level: general treatment, oral small molecular antiviral drugs, glucocorticoid, oxygen therapy and respiratory support.

　　Therefore, Zhang Wenhong emphasized that glucocorticoid should be used with great caution. It is suitable for COVID-19 patients with high-risk factors (older, with medium-sized clinical manifestations and evidence of disease progression). At this time, low-dose and short-term corticosteroids can be given. "Specific usage, you can use dexamethasone or prednisone, 4 ~ 6 tablets a day, eat for 3 days. Within 72 hours, the patient will face a turning point. If the patient gets better quickly, it will be reduced to 2-3 tablets and taken for another 3 days. If it is relieved later, either stop taking the medicine or use another tablet for 3-4 days. If the patient progresses to severe illness, he needs to be hospitalized for observation, and the dosage of hormones can also be increased, and the treatment plan for severe patients can be started later. "

　　"On the one hand, an early British clinical study showed that the daily use of 6 mg dexamethasone in large-scale hospitalized patients in COVID-19 can reduce the mortality rate; On the other hand, our team also gives patients low doses of hormones in the early stage of severe illness, which can greatly reduce the intubation rate of patients and reduce the mortality rate. " Zhang Wenhong said.

　　The Guide stipulates that glucocorticoid can be used for patients with early onset in the community, such as high-risk factors such as basic diseases and advanced age, or medium-sized patients who need oxygen therapy, after evaluating the contraindications of hormone use.

　　Zhang Wenhong said that "prone position ventilation treatment" for COVID-19 patients can be operated regardless of the resources of rural medical institutions, and it is suitable for medium-sized patients with severe high-risk factors and rapid progress. This is also recommended by many respiratory and critical care experts.

　　"When the patient is lying on his back, the heart and lungs are under certain pressure, and there will be problems in the proportion of ventilation blood flow. After prone, the pressure on the heart and lungs is reduced, the proportion of ventilation blood flow will be more balanced, and the physiological diseases related to inflammation of patients will also get better. " Li Yingchuan, an expert in critical care medicine and vice president of Shanghai Tenth People’s Hospital, explained to reporters earlier.

　 　 Special feature of 1905 film network Judging from the whole nomination situation, the Golden Globe Awards still follow the old way of "summarizer" in the award season. Still those familiar faces, or those familiar films, or a large and comprehensive nomination list. According to the trend of films in the award season, the number of awards won and the word-of-mouth of film critics, on the whole, and followed closely, while, and these three biographies are too safe and mainstream, and basically lose the chance to win the first prize. The alternative inspirational films, which have been popular since last year, are a little weak. Although the director Damien Chazelle became famous, he probably can’t do much.

　

　 　 There are 30 nominations for the performance category of the Golden Globe Awards, which is somewhat "chaotic". However, there are only a few popular actors who have the chance to win the prize. The situation of actor melee is more complicated. Everyone has the opportunity and strength. Among the actresses, Julianne Moore was shortlisted for two best actress awards with Starway, which is the candidate with the highest chance.

　

Best drama: 4/5 is the biography "Youth" still has the highest chance of winning.

　

　　　 Of the five films nominated for best drama, four are biographies. Selma tells a story about Martin Luther King, while The Imitation Game focuses on the legendary Turing. The protagonist of The Theory of Everything is Hawking. It is worth mentioning that after watching this movie, Hawking made it clear that he likes this movie very much, and although it was spit out by the prototype of the characters, as a movie, it is complete and full of emotions. Although it has a certain style tendency, it is somewhat far from ordinary fans, but it takes a lot of advantage in the award selection.

　

　　　 Among the five films, the only fictional film — — "Youth" is the most like a documentary. In pursuit of authenticity, film director richard linklater spent 12 years shooting this film. Waiting for the actor to grow up abruptly, filming the growth and change of an American youth from 6 to 18 years old. You can say that this is the director’s paranoia and his willfulness — — Of course, on the artistic level, this is the embodiment of a director’s ethics and execution.

　

　　　 According to the mainstream media in North America, "Youth" is unparalleled, not only because of the 12-year shooting time, but also because of the calm and indifferent texture conveyed in the film. In contrast, The Imitation Game is somewhat commercialized, while The Theory of Everything is like a love fairy tale, without the heavy feeling of winning the prize. Although The Fox Catcher is powerful, its restrained lens language and criticism of wealth still make the film not within the scope of mainstream values. Moreover, in recent days, the film has been "hated" by the protagonist prototype on social networking sites for seven times in a row, which is at the forefront of public opinion. Selma’s large-scale release time is very short, and its influence is limited. Moreover, it has already talked about racial issues last year, and the film theme is not dominant. Therefore, in terms of the best drama, "Youth" has the greatest chance of winning.

　

Best Music/Comedy: Birdman or Beating The Grand Budapest Hotel.

　

　　　 A small mix of geek comedies, gay movies and fairy tales is the second-tier film among the five nominated films in this award. First of all, the word-of-mouth of "Magic Black Forest" is quite general, and some media even think that the whole film is nothing except Meryl Streep’s performance. The remaining two films, although of acceptable standard, are indeed dispensable films in the award season. Apart from the Golden Globe Award, which lists comedy/music films separately, these two films are hard to find in the awards season. The remaining two films, Birdman and The Grand Budapest Hotel, are popular films in the award season. Moreover, the unique and unforgettable Birdman is very promising in the Oscar selection.

　

　　　 The Grand Budapest Hotel has a strong wes anderson style and is a unique work of this unique director. However, Anderson’s performance at the Golden Globe Award is very ordinary. This is his first nomination for the Golden Globe Award, and the chances of winning the award are not great, because those who were nominated for the Oscar before, and, all lost their trophies at the Golden Globe Award. Therefore, this "same recipe, same taste" film is hard to win at the Golden Globe Awards. Therefore, Bird Man, which is technically impeccable and has a strong "fantasy" plot, has become the film with the highest winning rate. Moreover, in this film, alejandro gonzalez inarritu also teased Hollywood by accident, showing his views on Hollywood as a Mexican "outsider". His view may win the favor of the Golden Globe Award hosted by hollywood foreign press association.

Best director: Richard Linkte’s 12-year sword-sharpening award is in sight.

　

　　　 There are only five nominated best director awards, which are the most variable and the most competitive. Linklater, the director of "Youth", used time, patience, emotion and execution to make a fictional film show the reality of documentary. The film thus gained an incredible texture. Although the three-hour-long film is a little dull and boring, it is as memorable as the taste of life. Especially the mother in the film, she said that after sending her two children away, she was waiting for her funeral, which was quite touching.

　

　　　 Birdman is full of whimsy. Although the clues of the story are old-fashioned, Inarito took the story to another level with his own means and skills of "turning ordinary into extraordinary". Although female directors ava duvernay, who filmed Selma, is 42 years old, she can be said to be a new director. Her outbreak this year has something to do with her accumulation in the circle for nearly ten years. Moreover, the black perspective and the film mixed with black street elements are refreshing.

　

　　　　 As for wes anderson and david fincher, they just contributed the films engraved with their style as always, without any breakthrough or innovation. This kind of directing work, at best, is called personal style; At worst, it is called standing still and standing still. Therefore, these two are not very competitive in the best director award. On the whole, richard linklater’s epic shooting process and extraordinary creativity are likely to win him the honor of best director.

next page　Performance awards: michael keaton and Julianne Moore have obvious advantages.

CCTV News:Yesterday (July 26th) afternoon, the State Council Press Office held a routine briefing on the State Council policy. It was introduced at the meeting that during the peak summer this year, China’s electricity, coal, natural gas and other supplies were fully prepared, ensuring the safe and stable supply of energy and electricity during the peak summer.

In terms of electricity, since the beginning of summer, the national daily dispatching power generation has reached a record high of 30.171 billion kWh, which is 1.511 billion kWh higher than last year’s peak. The highest electricity load in China has reached two record highs, reaching 1.339 billion kilowatts, 49.5 million kilowatts higher than last year’s peak. Under the complicated situation of rapid growth of demand and substantial reduction of hydropower generation, comprehensive measures have been taken to ensure the safe and stable supply of electricity throughout the country.

In terms of coal, since the beginning of this year, coal production has increased steadily, imports have increased rapidly, and coal supply and demand are generally balanced. Up to now, 198 million tons of coal has been stored in power plants nationwide, an increase of more than 23 million tons compared with the same period of last year, which can be used for nearly 26 days.

In terms of natural gas, production and import have maintained steady growth, effectively ensuring people’s livelihood and industrial and commercial gas needs.

　　　　　　 Ou Hong, Deputy Secretary General of the National Development and Reform Commission:According to dispatching statistics, the apparent consumption of natural gas in the first half of the year was 194.9 billion cubic meters, a year-on-year increase of 6.7%. Since the summer, the maximum power generation gas consumption per day has exceeded 250 million cubic meters, which has strongly supported the peak output of gas and electricity.

National Development and Reform Commission: Make use of hydropower resources to ensure power supply.

At yesterday’s briefing, the National Development and Reform Commission also introduced that by the end of June this year, China’s installed hydropower capacity had reached 420 million kilowatts, accounting for 15.4% of the total installed power. Various measures such as increasing water storage in advance have been taken to ensure hydropower generation.

Since July, the six cascade hydropower stations, such as Wudongde and Baihetan, on the main stream of the Yangtze River, have made sufficient water storage arrangements before, leaving enough peak power generation capacity. Therefore, on July 11th and 12th, the power generation output reached record highs, with the highest exceeding 32 million kilowatts, which played a key role in ensuring peak power supply.

The second is to strengthen multi-energy complementarity and improve the output level of thermal power and new energy. On the one hand, urge thermal power to be fully developed to ensure that the peak capacity of thermal power can be fully exerted; On the other hand, the construction of new energy sources has been increased. In the first half of this year, wind power generation and solar power generation increased by 16% and 7.4% respectively, forming an important supplement to power generation capacity.

In addition, give full play to the advantages of large power grids and help each other.

　　　　　　 Guan Peng, head of the Economic Operation Regulation Bureau of the National Development and Reform Commission:Faced with the shortage of hydropower output in southwest China, we have fully considered the supply and demand reality of sending and receiving provinces on the basis of stabilizing the power transmission scale all the year round, rationally optimized the relevant hydropower transmission arrangements, and at the same time, fully mobilized the resources of large power grids to increase the power transmission in northwest China, which has effectively supported the water storage and supply guarantee in southwest China.

National Energy Administration: By the end of June, the power transmission from West to East had exceeded 300 million kilowatts.

At the briefing held yesterday, the relevant person in charge of the National Energy Administration introduced that by the end of June, the transmission capacity of China’s "West-to-East Power Transmission" had exceeded 300 million kilowatts, which strongly supported the power supply guarantee work.

According to the relevant person in charge of the National Energy Administration, in order to ensure the supply of energy and electricity and optimize the layout of power supply in advance, by the end of June this year, the cumulative installed capacity of power generation in China was about 2.71 billion kilowatts, up 10.8% year-on-year. In the first half of the year, the installed capacity of various power sources put into operation and connected to the grid was about 140 million kilowatts, of which the supporting power supply was about 30 million kilowatts. At the same time, increase the planning and construction of transmission channels.

Liu Mingyang, Head of Electric Power Department of National Energy Administration:Since the beginning of this year, Baihetan — Zhejiang DC Project and Northern Shaanxi — Hubei DC supporting power supply project and other projects have been put into production one after another. By the end of June, the transmission capacity of China’s "West-to-East Power Transmission" has exceeded 300 million kilowatts, of which the maximum transmission capacity of inter-provincial and inter-regional DC channels during the summer can reach 180 million kilowatts, an increase of about 17.5 million kilowatts compared with the same period last year.

　　　　　　 At the same time, China has scientifically played the role of transmission channel. Since the beginning of summer, the scale of inter-provincial and inter-regional DC power transmission has reached a maximum of about 160 million kilowatts. Except that the incoming water of hydropower in southwest China is relatively dry and the power transmission capacity is optimized and reduced, the power transmission channels in North China, Northwest China, Northeast China and Yunnan-Guizhou basically send power according to the maximum transmission capacity, which effectively guarantees the power supply in heavy load periods such as East China, Central China and Guangdong.

Every time the AI news, on February 26th, the market news said that china galaxy and CICC planned to merge through share swap, which is expected to be announced in the next few weeks. In this regard, Xinhua Finance asked the two brokers for verification, and both public relations departments expressed ignorance. The above rumors have been reported many times in 2024, but they were denied by both companies. (Xinhua Finance)